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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iolmyo-Inositol + NAD+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADH + H+. (396 aa)    
Predicted Functional Partners:
iolE
IolE (Myo-inositol catabolism IolAEprotein) (Inosose dehydratase) (2-keto-myo-inositol dehydratase); Carbohydrate degradation, myo-inositol degradation to acetyl-CoA.
 
  0.905
CBL57833.1
Sugar (xylose) phosphate isomerase/epimerase.
 
    0.859
iolD
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing); Carbohydrate degradation, myo-inositol degradation to acetyl-CoA; Belongs to the TPP enzyme family.
 
  
 0.832
iolB
iolB (Myo-inositol catabolism IolB protein); Carbohydrate degradation, myo-inositol degradation to acetyl-CoA.
 
  
 0.820
iolH
iolG2 (Myo-inositol catabolism IolG2 protein) (Inositol 2-dehydrogenase); Inositol + NAD+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADH + H+.
 
    0.732
iolT2
iolT2 (myo-inositol transporter iolT2).
  
    0.728
lysS
Lysyl-tRNA synthetase; ATP + L-Lysine + tRNA(Lys) <=> AMP + Pyrophosphate + L-Lysyl-tRNA; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.528
iolC
iolC (Myo-inositol catabolism iolC protein); Carbohydrate degradation, myo-inositol degradation to acetyl-CoA.
 
    0.524
CBL57140.1
5.2 Protein of unknown function similar to proteins from other organisms.
  
  
 0.511
tal2
Transaldolase 2; Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.
 
  
 0.506
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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