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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acyPPutative acylphosphatase. (95 aa)    
Predicted Functional Partners:
pta
Acetyl-CoA + Orthophosphate <=> CoA + Acetyl phosphate / Propanoyl-CoA + Orthophosphate <=> Propanoyl phosphate + CoA.
    
 0.918
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.910
aldB
(S)-lactaldehyde + NAD(+) + H(2)O <=> (S)-lactate + NADH; Belongs to the aldehyde dehydrogenase family.
     
 0.902
cat
Coenzyme A transferase (Putative succinyl-CoA or butyryl-CoA:coenzyme A transferase); acyl-CoA + acetate = a fatty acid anion + acetyl-CoA OR: succinate + acetyl-CoA = succinyl-CoA + acetate OR (in Pf): succinate + propionyl-CoA = succinyl-CoA + propionate.
     
  0.900
CBL55977.1
Thiamine pyrophosphate enzyme; Belongs to the TPP enzyme family.
     
  0.900
nnrD
Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
 
     0.497
smc
Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family.
     
 0.446
nifJ2
Pyruvate:ferredoxin (Flavodoxin) oxidoreductase.
     
 0.403
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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