| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBL55552.1 | CBL57140.1 | PFREUD_00520 | PFREUD_16400 | Rhamnosyltransferase, Glycosyl transferase family 2; Transferring glycosyl groups. | 5.2 Protein of unknown function similar to proteins from other organisms. | 0.458 |
| CBL55552.1 | rmlA | PFREUD_00520 | PFREUD_00470 | Rhamnosyltransferase, Glycosyl transferase family 2; Transferring glycosyl groups. | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 0.687 |
| CBL55552.1 | rmlB | PFREUD_00520 | PFREUD_00550 | Rhamnosyltransferase, Glycosyl transferase family 2; Transferring glycosyl groups. | dTDP-glucose <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O / dTDP-glucose <=> 4,6-Dideoxy-4-oxo-dTDP-D-glucose + H2O; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.711 |
| CBL55552.1 | rmlC | PFREUD_00520 | PFREUD_00540 | Rhamnosyltransferase, Glycosyl transferase family 2; Transferring glycosyl groups. | dTDP-4-dehydrorhamnose reductase / dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. | 0.963 |
| CBL55552.1 | udgA | PFREUD_00520 | PFREUD_02540 | Rhamnosyltransferase, Glycosyl transferase family 2; Transferring glycosyl groups. | UDP-glucose + H2O + 2 NAD+ <=> UDP-glucuronate + 2 NADH + H+. | 0.549 |
| CBL57140.1 | CBL55552.1 | PFREUD_16400 | PFREUD_00520 | 5.2 Protein of unknown function similar to proteins from other organisms. | Rhamnosyltransferase, Glycosyl transferase family 2; Transferring glycosyl groups. | 0.458 |
| CBL57140.1 | rmlA | PFREUD_16400 | PFREUD_00470 | 5.2 Protein of unknown function similar to proteins from other organisms. | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 0.663 |
| CBL57140.1 | rmlB | PFREUD_16400 | PFREUD_00550 | 5.2 Protein of unknown function similar to proteins from other organisms. | dTDP-glucose <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O / dTDP-glucose <=> 4,6-Dideoxy-4-oxo-dTDP-D-glucose + H2O; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.802 |
| CBL57140.1 | rmlC | PFREUD_16400 | PFREUD_00540 | 5.2 Protein of unknown function similar to proteins from other organisms. | dTDP-4-dehydrorhamnose reductase / dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. | 0.816 |
| fimP | rmlB | PFREUD_19790 | PFREUD_00550 | Type-1 fimbrial major subunit precursor. | dTDP-glucose <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O / dTDP-glucose <=> 4,6-Dideoxy-4-oxo-dTDP-D-glucose + H2O; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.672 |
| ftsX | murE | PFREUD_09600 | PFREUD_15550 | Cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.672 |
| ftsX | rmlB | PFREUD_09600 | PFREUD_00550 | Cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | dTDP-glucose <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O / dTDP-glucose <=> 4,6-Dideoxy-4-oxo-dTDP-D-glucose + H2O; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.671 |
| ftsX | rmlC | PFREUD_09600 | PFREUD_00540 | Cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | dTDP-4-dehydrorhamnose reductase / dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. | 0.674 |
| glf, | rmlA | PFREUD_00570 | PFREUD_00470 | Molecular function: UDP-galactopyranose mutase activity, Biological process: lipopolysaccharide biosynthetic process. UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose. | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 0.902 |
| glf, | rmlB | PFREUD_00570 | PFREUD_00550 | Molecular function: UDP-galactopyranose mutase activity, Biological process: lipopolysaccharide biosynthetic process. UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose. | dTDP-glucose <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O / dTDP-glucose <=> 4,6-Dideoxy-4-oxo-dTDP-D-glucose + H2O; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.872 |
| glf, | rmlC | PFREUD_00570 | PFREUD_00540 | Molecular function: UDP-galactopyranose mutase activity, Biological process: lipopolysaccharide biosynthetic process. UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose. | dTDP-4-dehydrorhamnose reductase / dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. | 0.994 |
| glf, | udgA | PFREUD_00570 | PFREUD_02540 | Molecular function: UDP-galactopyranose mutase activity, Biological process: lipopolysaccharide biosynthetic process. UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose. | UDP-glucose + H2O + 2 NAD+ <=> UDP-glucuronate + 2 NADH + H+. | 0.892 |
| murE | ftsX | PFREUD_15550 | PFREUD_09600 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | Cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. | 0.672 |
| murE | rmlB | PFREUD_15550 | PFREUD_00550 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | dTDP-glucose <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O / dTDP-glucose <=> 4,6-Dideoxy-4-oxo-dTDP-D-glucose + H2O; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.685 |
| murE | rmlC | PFREUD_15550 | PFREUD_00540 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | dTDP-4-dehydrorhamnose reductase / dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. | 0.743 |