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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xylBXylulokinase protein, Carbohydrate kinase; ATP + D-Xylulose <=> ADP + D-Xylulose 5-phosphate. (518 aa)    
Predicted Functional Partners:
araD1
L-ribulokinase (ribulokinase); ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate. L-arabinose catabolism; second step. Transcription is repressed by glucose and by the binding of araR to the operon promoter. L-arabinose acts as an inducer by inhibiting the binding of araR to the DNA, thus allowing expression of the gene. Belongs to the ribulokinase family.
  
 
 0.945
araD
L-ribulose-5-phosphate 4-epimerase AraD; L-Ribulose 5-phosphate <=> D-Xylulose 5-phosphate.
  
 
 0.945
rpe
Ribulose-phosphate 3-epimerase; D-ribulose 5-phosphate = D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
 
 
 0.926
gpsA
Glycerol-3-phosphate dehydrogenase [NAD(P)+] (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase); sn-Glycerol 3-phosphate + NAD+ <=> Glycerone phosphate + NADH + H+ / sn-Glycerol 3-phosphate + NADP+ <=> Glycerone phosphate + NADPH + H+; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.781
araM
L-arabinose utilization protein.
 
   
 0.726
glpA
Anaerobic glycerol-3-phosphate dehydrogenase subunit A; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.703
pyk1
Pyruvate kinase 1; ATP + Pyruvate <=> ADP + Phosphoenolpyruvate; Belongs to the pyruvate kinase family.
     
 0.694
deoR1
Transcriptional regulator of sugar metabolism.
 
  
 0.626
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.591
araL
L-arabinose operon protein, hydrolase; Arabinose operon.
 
  
 0.578
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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