STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
deoR1Transcriptional regulator of sugar metabolism. (258 aa)    
Predicted Functional Partners:
xylB
Xylulokinase protein, Carbohydrate kinase; ATP + D-Xylulose <=> ADP + D-Xylulose 5-phosphate.
 
  
 0.626
gpsA
Glycerol-3-phosphate dehydrogenase [NAD(P)+] (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase); sn-Glycerol 3-phosphate + NAD+ <=> Glycerone phosphate + NADH + H+ / sn-Glycerol 3-phosphate + NADP+ <=> Glycerone phosphate + NADPH + H+; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
     0.618
pptE
Phosphoenolpyruvate-protein phosphoryltransferase PptE; Belongs to the PEP-utilizing enzyme family.
  
  
 0.468
kduD
2-deoxy-D-gluconate 3-dehydrogenase; 2-Dehydro-3-deoxy-D-gluconate + NAD+ <=> (4S)-4,6-Dihydroxy-2,5-dioxohexanoate + NADH + H+ and 2-Deoxy-D-gluconate + NAD+ <=> 3-Dehydro-2-deoxy-D-gluconate + NADH + H+.
  
    0.449
fabG
3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.449
CBL56987.1
Dehydrogenase.
  
    0.449
lacI3
The LacI family of proteins consist of transcriptional regulators related to the lac repressor. In this case, generally the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain.
  
   
 0.426
iolB
iolB (Myo-inositol catabolism IolB protein); Carbohydrate degradation, myo-inositol degradation to acetyl-CoA.
  
  
 0.424
lacI2
Transcriptional regulator, LacI family protein.
  
   
 0.418
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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