close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hflC1Gluconokinase; ATP + D-Gluconic acid <=> ADP + 6-Phospho-D-gluconate. (241 aa)    
Predicted Functional Partners:
ftsH
FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.837
CBL55601.1
Hypothetical protein; No peptide signal, 3 TM domains according to TMHMM.
 
     0.680
hflC2
Stomatin/prohibitin; Prokaryotic HflK/C plays a role in the decision between lysogenic and lytic cycle growth during lambda phage infection.
  
     0.596
CBL56723.1
Hypothetical membrane protein.
   
 0.567
CBL56490.1
5.2 Protein of unknown function similar to proteins from other organisms; Belongs to the UPF0301 (AlgH) family.
   
    0.564
norB
Nitric-oxide reductase subunit B (nitric-oxide reductase); Reduced acceptor + 2 Nitric oxide <=> Nitrous oxide + Acceptor + H2O / Nitric oxide + NADH + H+ <=> Nitrous oxide + NAD+ + H2O.
       0.520
CBL56522.1
Zn dependant peptidase.
   
 0.484
CBL56523.1
Zn-dependant peptidase.
   
 0.484
aatA
Leucyl/phenylalanyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
       0.460
CBL56969.1
Acetyltransferase family protein.
  
    0.445
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
Server load: low (30%) [HD]