STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBL55649.15.2 Protein of unknown function similar to proteins from other organisms. (367 aa)    
Predicted Functional Partners:
PPA1976
Para-aminobenzoate synthase.
  
  
 0.800
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.721
leuA1
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.589
leuA2
(2S)-2-Isopropylmalate + CoA <=> Acetyl-CoA + 3-Methyl-2-oxobutanoic acid + H2O; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.589
CBL55977.1
Thiamine pyrophosphate enzyme; Belongs to the TPP enzyme family.
  
 
 0.514
ilvB
Acetolactate synthase, large subunit, biosynthetic type; 2-Acetolactate + CO2 <=> 2 Pyruvate - Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.
  
 
 0.514
panE1
2-dehydropantoate 2-reductase (KPA reductase) (Ketopantoate reductase); Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
    0.493
thrC
Threonine synthase (O-phospho-L-homoserine phosphate-lyase (adding water;L-threonine-forming)); O-Phospho-L-homoserine + H2O <=> L-Threonine + Orthophosphate / O-Phospho-4-hydroxy-L-threonine + H2O <=> 4-Hydroxy-L-threonine + Orthophosphate.
 
 
 0.439
araC1
Helix-turn-helix, AraC type.
  
     0.437
ilvN
Acetolactate synthase subunit small; 2-Acetolactate + CO2 <=> 2 Pyruvate - Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.
  
 
 0.436
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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