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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsG/ptsMPTS system mannose-specific EIIBCA component (EIIBCA-Man) (EII-Man/EIII-Man). (990 aa)    
Predicted Functional Partners:
pptE
Phosphoenolpyruvate-protein phosphoryltransferase PptE; Belongs to the PEP-utilizing enzyme family.
 
 
 0.995
CBL57441.1
Phosphocarrier, HPr family; HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation across the cell membrane.
 
 0.973
CE1826,
PTS enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.838
glpK
Glycerol kinase (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
    
 
 0.825
manA
Phosphomannose isomerase; D-Mannose 6-phosphate <=> D-Fructose 6-phosphate and D-Mannose 6-phosphate <=> beta-D-Fructose 6-phosphate.
     
 0.752
pf435
Peptidase, S9C (Acylaminoacyl-peptidase) family.
    
 
 0.633
CBL57853.1
6 Protein of unknown function, without similarity to other proteins.
    
 
 0.553
CBL57876.1
Alpha-amylase; Starch + H2O <=> Dextrin + Starch.
 
  
 0.533
CBL57350.1
ABC transporter ATP-binding protein; Belongs to the ABC transporter superfamily.
   
 
 0.510
galT
Galactose-1-phosphate uridylyltransferase (UDP-glucose---hexose-1-phosphate uridylyltransferase); UDP-glucose + alpha-D-Galactose 1-phosphate <=> D-Glucose 1-phosphate + UDP-D-galactose.
  
   
 0.503
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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