| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| atpB | atpC | PFREUD_10430 | PFREUD_10500 | ATP synthase A chain (ATPase protein 6) (F1F0-ATPase subunit a); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.999 |
| atpB | cydA | PFREUD_10430 | PFREUD_01720 | ATP synthase A chain (ATPase protein 6) (F1F0-ATPase subunit a); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | Cytochrome d ubiquinol oxidase subunit I. | 0.443 |
| atpB | cydB | PFREUD_10430 | PFREUD_01730 | ATP synthase A chain (ATPase protein 6) (F1F0-ATPase subunit a); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | Cytochrome d ubiquinol oxidase, subunit II. | 0.543 |
| atpB | nuoH | PFREUD_10430 | PFREUD_05230 | ATP synthase A chain (ATPase protein 6) (F1F0-ATPase subunit a); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | NADH-quinone oxidoreductase subunit H (NADH dehydrogenase I subunit H); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. | 0.946 |
| atpB | nuoJ | PFREUD_10430 | PFREUD_05250 | ATP synthase A chain (ATPase protein 6) (F1F0-ATPase subunit a); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | NADH-quinone oxidoreductase chain J (NADH dehydrogenase I, chain J); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.422 |
| atpB | nuoK | PFREUD_10430 | PFREUD_05260 | ATP synthase A chain (ATPase protein 6) (F1F0-ATPase subunit a); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | NADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. | 0.456 |
| atpB | nuoL | PFREUD_10430 | PFREUD_05270 | ATP synthase A chain (ATPase protein 6) (F1F0-ATPase subunit a); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | NADH dehydrogenase (quinone); Acceptor + NADH + H+ <=> Reduced acceptor + NAD+. | 0.534 |
| atpB | nuoN | PFREUD_10430 | PFREUD_05290 | ATP synthase A chain (ATPase protein 6) (F1F0-ATPase subunit a); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | NADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. | 0.864 |
| atpC | atpB | PFREUD_10500 | PFREUD_10430 | ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane. | ATP synthase A chain (ATPase protein 6) (F1F0-ATPase subunit a); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | 0.999 |
| atpC | cydA | PFREUD_10500 | PFREUD_01720 | ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane. | Cytochrome d ubiquinol oxidase subunit I. | 0.556 |
| atpC | cydB | PFREUD_10500 | PFREUD_01730 | ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane. | Cytochrome d ubiquinol oxidase, subunit II. | 0.621 |
| atpC | nuoH | PFREUD_10500 | PFREUD_05230 | ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane. | NADH-quinone oxidoreductase subunit H (NADH dehydrogenase I subunit H); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. | 0.691 |
| atpC | nuoJ | PFREUD_10500 | PFREUD_05250 | ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane. | NADH-quinone oxidoreductase chain J (NADH dehydrogenase I, chain J); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.437 |
| atpC | nuoK | PFREUD_10500 | PFREUD_05260 | ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane. | NADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. | 0.556 |
| atpC | nuoL | PFREUD_10500 | PFREUD_05270 | ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane. | NADH dehydrogenase (quinone); Acceptor + NADH + H+ <=> Reduced acceptor + NAD+. | 0.562 |
| atpC | nuoN | PFREUD_10500 | PFREUD_05290 | ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane. | NADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. | 0.605 |
| atpC | sdhA | PFREUD_10500 | PFREUD_09250 | ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane. | # Succinate + FAD <=> FADH2 + Fumarate, A flavoprotein (FAD) containing iron-sulfur centres. A component of EC 1.3.5.1 succinate dehydrogenase (ubiquinone). | 0.687 |
| cydA | atpB | PFREUD_01720 | PFREUD_10430 | Cytochrome d ubiquinol oxidase subunit I. | ATP synthase A chain (ATPase protein 6) (F1F0-ATPase subunit a); Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. | 0.443 |
| cydA | atpC | PFREUD_01720 | PFREUD_10500 | Cytochrome d ubiquinol oxidase subunit I. | ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.556 |
| cydA | cydB | PFREUD_01720 | PFREUD_01730 | Cytochrome d ubiquinol oxidase subunit I. | Cytochrome d ubiquinol oxidase, subunit II. | 0.999 |