Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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caiACrotonobetainyl-CoA dehydrogenase (Crotonobetainyl-CoA reductase); Fatty acid metabolism and xenobiotic degradation. (378 aa)    
Predicted Functional Partners:
fixB
Electron transfer flavoprotein, carnitine metabolism (FixB protein); Required for anaerobic carnitine reduction. May bring reductant to caiA.
 
 0.997
fixA
Electron transfer flavoprotein (FixA protein); Required for anaerobic carnitine reduction. May bring reductant to caiA.
 
 
 0.969
caiD
Enoyl-CoA hydratase/carnithine racemase CaiD.
 
 0.955
maoC
MaoC acyl dehydratase.
 
 0.935
caiB
Crotonobetainyl-CoA:carnitine CoA-transferase; Engemann et al. Cai locus and corresponding enzymes of Proteus sp; Belongs to the CoA-transferase III family.
 
 
 0.931
mmgA
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA and Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.930
caiC
Crotonobetaine/carnitine-CoA ligase; Could catalyze the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the caiB reaction cycle.
 
  
 0.877
fixX
Ferredoxin-like protein fixX.
 
 
 0.807
fixC
Electron transfer flavoprotein-quinone oxidoreductase (FixC protein).
 
  
 0.782
nifJ1
Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase, Pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin.
  
  
 0.704
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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