STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fixAElectron transfer flavoprotein (FixA protein); Required for anaerobic carnitine reduction. May bring reductant to caiA. (251 aa)    
Predicted Functional Partners:
fixB
Electron transfer flavoprotein, carnitine metabolism (FixB protein); Required for anaerobic carnitine reduction. May bring reductant to caiA.
 
 0.999
fixX
Ferredoxin-like protein fixX.
 
 0.997
caiA
Crotonobetainyl-CoA dehydrogenase (Crotonobetainyl-CoA reductase); Fatty acid metabolism and xenobiotic degradation.
 
 
 0.978
fixC
Electron transfer flavoprotein-quinone oxidoreductase (FixC protein).
 
 
 0.967
fad
Acyl-CoA dehydrogenase.
 
 
 0.918
caiB
Crotonobetainyl-CoA:carnitine CoA-transferase; Engemann et al. Cai locus and corresponding enzymes of Proteus sp; Belongs to the CoA-transferase III family.
 
 
 
 0.828
nifJ1
Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase, Pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin.
  
 
 0.822
Arth_4141
FAD linked oxidase domain protein.
  
 
 0.730
CBL56331.1
Oxidoreductase.
  
 
 0.730
nuoI
NADH-quinone oxidoreductase subunit I (NADH dehydrogenase I subunit I) (NDH-1 subunit I); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.716
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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