Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
udgAUDP-glucose + H2O + 2 NAD+ <=> UDP-glucuronate + 2 NADH + H+. (472 aa)    
Predicted Functional Partners:
rmlA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.988
rmlC
dTDP-4-dehydrorhamnose reductase / dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
  
  
 0.972
sqdB
UDP-sulfoquinovose synthase; UDP-glucose + HSO3- <=> UDP-6-sulfoquinovose + H2O.
  
 0.932
galE3
UDP-glucose 4-epimerase.
 
 
 0.925
galE1
UDP-glucose = UDP-galactose.
 
 
 0.924
galE2
# UDP-glucose <=> UDP-D-galactose dTDP-glucose <=> dTDP-galactose.
 
 
 0.924
glf,
Molecular function: UDP-galactopyranose mutase activity, Biological process: lipopolysaccharide biosynthetic process. UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose.
  
  
 0.916
ugpA
UTP--glucose-1-phosphate uridylyltransferase; UTP + D-Glucose 1-phosphate <=> Pyrophosphate + UDP-glucose.
   
 
 0.910
manC
Mannose-1-phosphate guanylyltransferase.
 
 
 0.903
rmlB
dTDP-glucose <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O / dTDP-glucose <=> 4,6-Dideoxy-4-oxo-dTDP-D-glucose + H2O; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.876
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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