STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkBCarbohydrate kinase, PfkB. (334 aa)    
Predicted Functional Partners:
codB
Permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family.
 
     0.885
iunH
Inosine/uridine-preferring nucleoside hydrolase (purine nucleosidase); Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base.
 
  
 0.673
iolB
iolB (Myo-inositol catabolism IolB protein); Carbohydrate degradation, myo-inositol degradation to acetyl-CoA.
  
  
 0.594
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)- 1-(5-phosphoribosyl)imidazole-4-carboxamide.
  
    0.565
frk
Fructokinase; ATP + D-Fructose <=> ADP + D-Fructose 6-phosphate.
  
     0.557
iolD
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing); Carbohydrate degradation, myo-inositol degradation to acetyl-CoA; Belongs to the TPP enzyme family.
  
  
 0.537
nifJ2
Pyruvate:ferredoxin (Flavodoxin) oxidoreductase.
   
 
 0.521
CBL55797.1
6 Protein of unknown function, without similarity to other proteins.
       0.478
CBL55798.1
6 Protein of unknown function, without similarity to other proteins.
       0.478
dcm
S-Adenosyl-L-methionine + DNA <=> S-Adenosyl-L-homocysteine + DNA 5-methylcytosine and S-Adenosyl-L-methionine + DNA cytosine <=> S-Adenosyl-L-homocysteine + DNA 5-methylcytosine.
       0.478
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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