| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBL56146.1 | cbiE | PFREUD_06160 | PFREUD_07700 | ABC transporter-associated permease. | Precorrin methylase (precorrin-3B C17-methyltransferase) CbiE/G/H fusion protein; S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4 / Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine. | 0.829 |
| CBL56146.1 | cbiM | PFREUD_06160 | PFREUD_04590 | ABC transporter-associated permease. | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. | 0.740 |
| CBL56146.1 | cbiN | PFREUD_06160 | PFREUD_04580 | ABC transporter-associated permease. | CbiN is part of the active cobalt transport system involved in uptake of cobalt in to the cell involved with cobalamin biosynthesis (vitamin B12). | 0.479 |
| CBL56146.1 | cbiO1 | PFREUD_06160 | PFREUD_04560 | ABC transporter-associated permease. | Cobalt import ATP-binding protein CbiO; Part of an ABC transporter complex. Responsible for energy coupling to the transport system. | 0.641 |
| CBL56146.1 | cbiQ1 | PFREUD_06160 | PFREUD_20200 | ABC transporter-associated permease. | ABC-type transporter, permease components (ABC-type cobalt transport system, permease component CbiQ). | 0.900 |
| CBL56886.1 | cbiE | PFREUD_13690 | PFREUD_07700 | Cobalt permease. | Precorrin methylase (precorrin-3B C17-methyltransferase) CbiE/G/H fusion protein; S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4 / Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine. | 0.803 |
| CBL56886.1 | cbiM | PFREUD_13690 | PFREUD_04590 | Cobalt permease. | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. | 0.740 |
| CBL56886.1 | cbiN | PFREUD_13690 | PFREUD_04580 | Cobalt permease. | CbiN is part of the active cobalt transport system involved in uptake of cobalt in to the cell involved with cobalamin biosynthesis (vitamin B12). | 0.479 |
| CBL56886.1 | cbiO1 | PFREUD_13690 | PFREUD_04560 | Cobalt permease. | Cobalt import ATP-binding protein CbiO; Part of an ABC transporter complex. Responsible for energy coupling to the transport system. | 0.641 |
| CbiJ | cbiE | PFREUD_07760 | PFREUD_07700 | Precorrin-6x reductase CbiJ; # Precorrin 6Y + NADP+ <=> Precorrin 6X + NADPH + H+. | Precorrin methylase (precorrin-3B C17-methyltransferase) CbiE/G/H fusion protein; S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4 / Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine. | 0.999 |
| CbiJ | cbiM | PFREUD_07760 | PFREUD_04590 | Precorrin-6x reductase CbiJ; # Precorrin 6Y + NADP+ <=> Precorrin 6X + NADPH + H+. | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. | 0.736 |
| CbiJ | cysG/cbiX | PFREUD_07760 | PFREUD_07710 | Precorrin-6x reductase CbiJ; # Precorrin 6Y + NADP+ <=> Precorrin 6X + NADPH + H+. | CysG/CbiX; Cobalt fixation on precorrin 2. | 0.863 |
| cbiE | CBL56146.1 | PFREUD_07700 | PFREUD_06160 | Precorrin methylase (precorrin-3B C17-methyltransferase) CbiE/G/H fusion protein; S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4 / Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine. | ABC transporter-associated permease. | 0.829 |
| cbiE | CBL56886.1 | PFREUD_07700 | PFREUD_13690 | Precorrin methylase (precorrin-3B C17-methyltransferase) CbiE/G/H fusion protein; S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4 / Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine. | Cobalt permease. | 0.803 |
| cbiE | CbiJ | PFREUD_07700 | PFREUD_07760 | Precorrin methylase (precorrin-3B C17-methyltransferase) CbiE/G/H fusion protein; S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4 / Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine. | Precorrin-6x reductase CbiJ; # Precorrin 6Y + NADP+ <=> Precorrin 6X + NADPH + H+. | 0.999 |
| cbiE | cbiM | PFREUD_07700 | PFREUD_04590 | Precorrin methylase (precorrin-3B C17-methyltransferase) CbiE/G/H fusion protein; S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4 / Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine. | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. | 0.966 |
| cbiE | cbiN | PFREUD_07700 | PFREUD_04580 | Precorrin methylase (precorrin-3B C17-methyltransferase) CbiE/G/H fusion protein; S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4 / Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine. | CbiN is part of the active cobalt transport system involved in uptake of cobalt in to the cell involved with cobalamin biosynthesis (vitamin B12). | 0.964 |
| cbiE | cbiO1 | PFREUD_07700 | PFREUD_04560 | Precorrin methylase (precorrin-3B C17-methyltransferase) CbiE/G/H fusion protein; S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4 / Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine. | Cobalt import ATP-binding protein CbiO; Part of an ABC transporter complex. Responsible for energy coupling to the transport system. | 0.791 |
| cbiE | cbiQ1 | PFREUD_07700 | PFREUD_20200 | Precorrin methylase (precorrin-3B C17-methyltransferase) CbiE/G/H fusion protein; S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4 / Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine. | ABC-type transporter, permease components (ABC-type cobalt transport system, permease component CbiQ). | 0.803 |
| cbiE | cbiQ2 | PFREUD_07700 | PFREUD_04570 | Precorrin methylase (precorrin-3B C17-methyltransferase) CbiE/G/H fusion protein; S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4 / Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine. | Cobalt transport protein CbiQ. | 0.848 |