STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pabCBranched-chain amino acid aminotransferase/aminodeoxychorismate lyase. (290 aa)    
Predicted Functional Partners:
pabA
Glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase; Chorismate + NH3 <=> Anthranilate + Pyruvate + H2O Chorismate + L-Glutamine <=> Anthranilate + Pyruvate + L-Glutamate.
  
 
 0.922
folP1
Dihydropteroate synthase; 2-Amino-4-hydroxy-6-hydroxymethyl-7, 8-dihydropteridine + 4-Aminobenzoate <=> Dihydropteroate + H2O / 2-Amino-7, 8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine + 4-Aminobenzoate <=> Pyrophosphate + Dihydropteroate.
  
 
 0.913
folP2
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
 
 0.913
PPA1976
Para-aminobenzoate synthase.
  
 
 0.911
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.755
leuA1
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.589
leuA2
(2S)-2-Isopropylmalate + CoA <=> Acetyl-CoA + 3-Methyl-2-oxobutanoic acid + H2O; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.589
int-18
Integrase, catalytic region; Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome.
       0.524
CBL55977.1
Thiamine pyrophosphate enzyme; Belongs to the TPP enzyme family.
  
 
 0.514
ilvB
Acetolactate synthase, large subunit, biosynthetic type; 2-Acetolactate + CO2 <=> 2 Pyruvate - Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.
  
 
 0.514
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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