STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBL56121.1NAD(P)H-dependent FMN reductase. (215 aa)    
Predicted Functional Partners:
mer
Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase; 5,10-Methylenetetrahydromethanopterin + Coenzyme F420 <=> 5,10-Methenyltetrahydromethanopterin + Reduced coenzyme F420.
 
 0.985
cysH
Putative phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
   
 
 0.920
ribF
Riboflavin biosynthesis protein (Riboflavin kinase) FAD synthetase; ATP + FMN <=> Pyrophosphate + FAD / ATP + Riboflavin <=> ADP + FMN; Belongs to the ribF family.
    
 0.913
nirA2/sir2
Sulfite reductase [ferredoxin]; Hydrogen sulfide + 6 oxidized ferredoxin + 3 H2O = sulfite + 6 reduced ferredoxin + 6 H+.Binds 1 siroheme per subunit Binds 1 4Fe-4S cluster per subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
   
 
 0.911
sseB
Thiosulfate + Cyanide <=> Sulfite + Thiocyanate.
     
  0.900
bluB/cobT2
Phosphoribosyltransferase/nitroreductase (fusion gene) (Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase).
    
 0.652
ribAB
GTP cyclohydrolase II protein, Riboflavin biosynthesis protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
     
 0.517
CBL56625.1
Transporter.
  
  
 0.500
CBL56338.1
DSBA-like thioredoxin.
  
    0.410
frnE
Protein-disulfide isomerase (DSBA oxidoreductase).
  
    0.410
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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