STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBL56263.1Cell envelope-related transcriptional attenuator. (452 aa)    
Predicted Functional Partners:
arsR4
Transcriptional regulator, ArsR family.
  
    0.734
npdA
Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
   
    0.667
CBL56228.1
Silent information regulator protein Sir2 NAD-dependent deacetylase; Atalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+, producing nicotinamide and the novel metabolite O-acetyl-ADP-ribose. shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span.
   
    0.667
CBL56621.1
AsnC-family transcriptional regulatory protein.
   
    0.657
CBL56390.1
6 Protein of unknown function, without similarity to other proteins.
 
     0.580
manC
Mannose-1-phosphate guanylyltransferase.
       0.551
CBL57397.1
GntR-family protein transcriptional regulator.
   
    0.550
sirR
Iron dependent repressor.
   
    0.550
CBL56265.1
Hypothetical membrane protein.
       0.535
tagO
Undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; Catalyzes the formation of undecaprenyl-PP-N-acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to the peptidoglycan of B.subtilis. UDP-N-acetyl-D-glucosamine + undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyldiphospho-undecaprenol.
 
  
 0.525
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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