STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
araDL-ribulose-5-phosphate 4-epimerase AraD; L-Ribulose 5-phosphate <=> D-Xylulose 5-phosphate. (230 aa)    
Predicted Functional Partners:
araA
L-arabinose isomerase (L-arabinose aldose-ketose-isomerase); Catalyzes the conversion of L-arabinose to L-ribulose.
 
 
 0.992
araB
L-ribulokinase; ATP + Ribulose <=> ADP + D-Ribulose 5-phosphate; Belongs to the ribulokinase family.
 
 
 0.989
xylB
Xylulokinase protein, Carbohydrate kinase; ATP + D-Xylulose <=> ADP + D-Xylulose 5-phosphate.
  
 
 0.945
araD1
L-ribulokinase (ribulokinase); ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate. L-arabinose catabolism; second step. Transcription is repressed by glucose and by the binding of araR to the operon promoter. L-arabinose acts as an inducer by inhibiting the binding of araR to the DNA, thus allowing expression of the gene. Belongs to the ribulokinase family.
  
  
0.909
rpe
Ribulose-phosphate 3-epimerase; D-ribulose 5-phosphate = D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
     
 0.909
CBL57794.1
Hexulose-6-phosphate isomerase.
  
 
  0.903
CbiJ
Precorrin-6x reductase CbiJ; # Precorrin 6Y + NADP+ <=> Precorrin 6X + NADPH + H+.
       0.773
araM
L-arabinose utilization protein.
  
  
 0.758
citE
Citrate lyase beta chain (Citrase beta chain) (Citrate(Pro-3S)-lyase beta chain); Citrate <=> Acetate + Oxaloacetate / (3S)-Citryl-CoA <=> Acetyl-CoA + Oxaloacetate; Belongs to the HpcH/HpaI aldolase family.
   
    0.732
araL
L-arabinose operon protein, hydrolase; Arabinose operon.
  
  
 0.678
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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