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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dhaLPTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL; Complexation with ADP increases the thermal unfolding temperature from 40 to 65 degrees Celsius ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL-ADP receives a phosphoryl group from dhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sensor domain of dhaR. DhaL-ATP is inactive. (209 aa)    
Predicted Functional Partners:
dhaK
DhaK PTS-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit; ATP + Glycerone <=> ADP + Glycerone phosphate.
  
 0.999
pptE
Phosphoenolpyruvate-protein phosphoryltransferase PptE; Belongs to the PEP-utilizing enzyme family.
 
 
 0.995
araM
L-arabinose utilization protein.
  
 
 0.825
glpA
Anaerobic glycerol-3-phosphate dehydrogenase subunit A; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
    
 0.820
gpsA
Glycerol-3-phosphate dehydrogenase [NAD(P)+] (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase); sn-Glycerol 3-phosphate + NAD+ <=> Glycerone phosphate + NADH + H+ / sn-Glycerol 3-phosphate + NADP+ <=> Glycerone phosphate + NADPH + H+; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
   
 
 0.807
glpC
Anaerobic glycerol-3-phosphate dehydrogenase subunit C; Composed of a catalytic glpA/B dimer and of glpC. Electron transfer protein; may also function as the membrane anchor for the glpAB dimer.
     
  0.800
glpB
Anaerobic glycerol-3-phosphate dehydrogenase subunit B; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor. sn-glycerol 3-phosphate + acceptor = glycerone phosphate + reduced acceptor.
     
  0.800
CBL56324.1
ABC transporter ATP-binding protein.
       0.460
glpF
Glycerol uptake facilitator protein; FUNCTION: Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane (By similarity). # DOMAIN: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA); Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
  
 0.416
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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