Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBL56333.1Long-chain fatty-acid CoA ligase (AMP-binding enzyme) (long-chain-fatty-acid---CoA ligase); ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Pyrophosphate / ATP + Long-chain carboxylate + CoA <=> AMP + Pyrophosphate + Acyl-CoA. (629 aa)    
Predicted Functional Partners:
PPA2234
Putative long-chain-fatty-acid--CoA ligase/synthetase; ATP + Long-chain carboxylate + CoA <=> AMP + Pyrophosphate + Acyl-CoA and ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Pyrophosphate.
  
  
 
0.923
pf2652
5.2 Protein of unknown function similar to proteins from other organisms.
 
  
 0.873
accA
ATP + acetyl-CoA + HCO(3)(-) <=> ADP + phosphate + malonyl-CoA.
  
 
 0.811
pccB
Propionyl-CoA carboxylase beta chain; ATP + propanoyl-CoA + HCO(3)(-) <=> ADP + phosphate + (S)-methylmalonyl-CoA.
    
  0.802
fad
Acyl-CoA dehydrogenase.
  
 0.634
CBL56331.1
Oxidoreductase.
  
   0.596
acs
Fatty-acyl-CoA synthase; Acetyl-CoA <=> Long-chain acyl-CoA.
 
 
 0.577
marR1-2
Pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.
       0.571
caiD
Enoyl-CoA hydratase/carnithine racemase CaiD.
 
 
 0.445
moe
UBA/THIF-type NAD/FAD binding protein; Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family.
   
   0.440
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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