Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| asd | ask | PFREUD_20100 | PFREUD_03880 | Aspartate-semialdehyde dehydrogenase (Semialdehyde dehydrogenase); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aspartokinase (Aspartate kinase); ATP + L-Aspartate <=> ADP + 4-Phospho-L-aspartate; Belongs to the aspartokinase family. | 0.996 |
| asd | gltB | PFREUD_20100 | PFREUD_11860 | Aspartate-semialdehyde dehydrogenase (Semialdehyde dehydrogenase); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | 0.858 |
| asd | ilvA | PFREUD_20100 | PFREUD_03750 | Aspartate-semialdehyde dehydrogenase (Semialdehyde dehydrogenase); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.498 |
| asd | serC | PFREUD_20100 | PFREUD_18160 | Aspartate-semialdehyde dehydrogenase (Semialdehyde dehydrogenase); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Phosphoserine aminotransferase (phosphoserine transaminase); Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.437 |
| asd | thrA/hom | PFREUD_20100 | PFREUD_10320 | Aspartate-semialdehyde dehydrogenase (Semialdehyde dehydrogenase); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | L-Homoserine + NAD+ <=> L-Aspartate 4-semialdehyde + NADH + H+ and L-Homoserine + NADP+ <=> L-Aspartate 4-semialdehyde + NADPH + H+. | 0.990 |
| asd | thrC | PFREUD_20100 | PFREUD_08280 | Aspartate-semialdehyde dehydrogenase (Semialdehyde dehydrogenase); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Threonine synthase (O-phospho-L-homoserine phosphate-lyase (adding water;L-threonine-forming)); O-Phospho-L-homoserine + H2O <=> L-Threonine + Orthophosphate / O-Phospho-4-hydroxy-L-threonine + H2O <=> 4-Hydroxy-L-threonine + Orthophosphate. | 0.719 |
| ask | asd | PFREUD_03880 | PFREUD_20100 | Aspartokinase (Aspartate kinase); ATP + L-Aspartate <=> ADP + 4-Phospho-L-aspartate; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase (Semialdehyde dehydrogenase); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.996 |
| ask | gltB | PFREUD_03880 | PFREUD_11860 | Aspartokinase (Aspartate kinase); ATP + L-Aspartate <=> ADP + 4-Phospho-L-aspartate; Belongs to the aspartokinase family. | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | 0.612 |
| ask | ilvA | PFREUD_03880 | PFREUD_03750 | Aspartokinase (Aspartate kinase); ATP + L-Aspartate <=> ADP + 4-Phospho-L-aspartate; Belongs to the aspartokinase family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.430 |
| ask | thrA/hom | PFREUD_03880 | PFREUD_10320 | Aspartokinase (Aspartate kinase); ATP + L-Aspartate <=> ADP + 4-Phospho-L-aspartate; Belongs to the aspartokinase family. | L-Homoserine + NAD+ <=> L-Aspartate 4-semialdehyde + NADH + H+ and L-Homoserine + NADP+ <=> L-Aspartate 4-semialdehyde + NADPH + H+. | 0.959 |
| ask | thrC | PFREUD_03880 | PFREUD_08280 | Aspartokinase (Aspartate kinase); ATP + L-Aspartate <=> ADP + 4-Phospho-L-aspartate; Belongs to the aspartokinase family. | Threonine synthase (O-phospho-L-homoserine phosphate-lyase (adding water;L-threonine-forming)); O-Phospho-L-homoserine + H2O <=> L-Threonine + Orthophosphate / O-Phospho-4-hydroxy-L-threonine + H2O <=> 4-Hydroxy-L-threonine + Orthophosphate. | 0.843 |
| gltB | asd | PFREUD_11860 | PFREUD_20100 | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | Aspartate-semialdehyde dehydrogenase (Semialdehyde dehydrogenase); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.858 |
| gltB | ask | PFREUD_11860 | PFREUD_03880 | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | Aspartokinase (Aspartate kinase); ATP + L-Aspartate <=> ADP + 4-Phospho-L-aspartate; Belongs to the aspartokinase family. | 0.612 |
| gltB | ilvA | PFREUD_11860 | PFREUD_03750 | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.862 |
| gltB | ilvC | PFREUD_11860 | PFREUD_13390 | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.895 |
| gltB | leuD | PFREUD_11860 | PFREUD_13270 | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.802 |
| gltB | thrA/hom | PFREUD_11860 | PFREUD_10320 | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | L-Homoserine + NAD+ <=> L-Aspartate 4-semialdehyde + NADH + H+ and L-Homoserine + NADP+ <=> L-Aspartate 4-semialdehyde + NADPH + H+. | 0.803 |
| gltB | thrC | PFREUD_11860 | PFREUD_08280 | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | Threonine synthase (O-phospho-L-homoserine phosphate-lyase (adding water;L-threonine-forming)); O-Phospho-L-homoserine + H2O <=> L-Threonine + Orthophosphate / O-Phospho-4-hydroxy-L-threonine + H2O <=> 4-Hydroxy-L-threonine + Orthophosphate. | 0.708 |
| ilvA | asd | PFREUD_03750 | PFREUD_20100 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Aspartate-semialdehyde dehydrogenase (Semialdehyde dehydrogenase); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.498 |
| ilvA | ask | PFREUD_03750 | PFREUD_03880 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Aspartokinase (Aspartate kinase); ATP + L-Aspartate <=> ADP + 4-Phospho-L-aspartate; Belongs to the aspartokinase family. | 0.430 |
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