| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBL56361.1 | dsbG | PFREUD_08340 | PFREUD_08330 | Hypothetical membrane protein. | DSBA oxidoreductase; Protein-disulfide isomerase. | 0.734 |
| cbiF | cbiM | PFREUD_07690 | PFREUD_04590 | CbiF Precorrin-4 C11-methyltransferase; # S-Adenosyl-L-methionine + Precorrin 4 <=> S-Adenosyl-L-homocysteine + Precorrin 5. | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. | 0.660 |
| cbiF | cbiN | PFREUD_07690 | PFREUD_04580 | CbiF Precorrin-4 C11-methyltransferase; # S-Adenosyl-L-methionine + Precorrin 4 <=> S-Adenosyl-L-homocysteine + Precorrin 5. | CbiN is part of the active cobalt transport system involved in uptake of cobalt in to the cell involved with cobalamin biosynthesis (vitamin B12). | 0.792 |
| cbiF | cysG/cbiX | PFREUD_07690 | PFREUD_07710 | CbiF Precorrin-4 C11-methyltransferase; # S-Adenosyl-L-methionine + Precorrin 4 <=> S-Adenosyl-L-homocysteine + Precorrin 5. | CysG/CbiX; Cobalt fixation on precorrin 2. | 0.989 |
| cbiF | dsbG | PFREUD_07690 | PFREUD_08330 | CbiF Precorrin-4 C11-methyltransferase; # S-Adenosyl-L-methionine + Precorrin 4 <=> S-Adenosyl-L-homocysteine + Precorrin 5. | DSBA oxidoreductase; Protein-disulfide isomerase. | 0.659 |
| cbiF | frnE | PFREUD_07690 | PFREUD_16760 | CbiF Precorrin-4 C11-methyltransferase; # S-Adenosyl-L-methionine + Precorrin 4 <=> S-Adenosyl-L-homocysteine + Precorrin 5. | Protein-disulfide isomerase (DSBA oxidoreductase). | 0.673 |
| cbiF | hemK | PFREUD_07690 | PFREUD_10370 | CbiF Precorrin-4 C11-methyltransferase; # S-Adenosyl-L-methionine + Precorrin 4 <=> S-Adenosyl-L-homocysteine + Precorrin 5. | Methylase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.659 |
| cbiF | hemY | PFREUD_07690 | PFREUD_18930 | CbiF Precorrin-4 C11-methyltransferase; # S-Adenosyl-L-methionine + Precorrin 4 <=> S-Adenosyl-L-homocysteine + Precorrin 5. | Protoporphyrinogen oxidase (PPO) HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.656 |
| cbiF | nrdJ | PFREUD_07690 | PFREUD_13010 | CbiF Precorrin-4 C11-methyltransferase; # S-Adenosyl-L-methionine + Precorrin 4 <=> S-Adenosyl-L-homocysteine + Precorrin 5. | Vitamin B12-dependent ribonucleotide reductase (Ribonucleoside-diphosphate reductase NrdJ); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.664 |
| cbiF | sufB | PFREUD_07690 | PFREUD_14980 | CbiF Precorrin-4 C11-methyltransferase; # S-Adenosyl-L-methionine + Precorrin 4 <=> S-Adenosyl-L-homocysteine + Precorrin 5. | FeS assembly protein SufB. | 0.651 |
| cbiM | cbiF | PFREUD_04590 | PFREUD_07690 | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. | CbiF Precorrin-4 C11-methyltransferase; # S-Adenosyl-L-methionine + Precorrin 4 <=> S-Adenosyl-L-homocysteine + Precorrin 5. | 0.660 |
| cbiM | cbiN | PFREUD_04590 | PFREUD_04580 | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. | CbiN is part of the active cobalt transport system involved in uptake of cobalt in to the cell involved with cobalamin biosynthesis (vitamin B12). | 0.998 |
| cbiM | cysG/cbiX | PFREUD_04590 | PFREUD_07710 | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. | CysG/CbiX; Cobalt fixation on precorrin 2. | 0.727 |
| cbiM | dsbG | PFREUD_04590 | PFREUD_08330 | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. | DSBA oxidoreductase; Protein-disulfide isomerase. | 0.655 |
| cbiM | frnE | PFREUD_04590 | PFREUD_16760 | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. | Protein-disulfide isomerase (DSBA oxidoreductase). | 0.655 |
| cbiM | hemK | PFREUD_04590 | PFREUD_10370 | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. | Methylase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.655 |
| cbiM | hemY | PFREUD_04590 | PFREUD_18930 | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. | Protoporphyrinogen oxidase (PPO) HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.627 |
| cbiM | nrdJ | PFREUD_04590 | PFREUD_13010 | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. | Vitamin B12-dependent ribonucleotide reductase (Ribonucleoside-diphosphate reductase NrdJ); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.656 |
| cbiM | sufB | PFREUD_04590 | PFREUD_14980 | Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. | FeS assembly protein SufB. | 0.401 |
| cbiN | cbiF | PFREUD_04580 | PFREUD_07690 | CbiN is part of the active cobalt transport system involved in uptake of cobalt in to the cell involved with cobalamin biosynthesis (vitamin B12). | CbiF Precorrin-4 C11-methyltransferase; # S-Adenosyl-L-methionine + Precorrin 4 <=> S-Adenosyl-L-homocysteine + Precorrin 5. | 0.792 |