STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPA1112Uncharacterized protein probably involved in trehalose biosynthesis. (445 aa)    
Predicted Functional Partners:
treS
Trehalose synthase; Catalyzes the conversion of maltose into alpha,alpha-trehalose by transglucosylation. Annotated from blastp from sequence of (Cardoso et al, 2007 PubMed 17185556).
 0.999
glgE
Glycosyl hydrolase, family 13 (putative alpha-amylase, catalytic domain); Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
 
 0.999
glgB
1,4-alpha-glucan branching enzyme GlgB; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
  
 0.994
aglA
Alpha-1,4-glucosidase.
 0.992
CBL57876.1
Alpha-amylase; Starch + H2O <=> Dextrin + Starch.
 
 0.961
malQ1
4-alpha-glucanotransferase (Amylomaltase) (Disproportionating enzyme) (D-enzyme); Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.
 
 
 0.954
malQ2
4-alpha-glucanotransferase (Amylomaltase) (Disproportionating enzyme) (D-enzyme); Amylose <=> 1,4-alpha-D-Glucan.
 
 
 0.952
glgA
Glycosyltransferase (glycogen synthase); ADP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase.
  
  
 0.946
glgP
Alpha-glucan phosphorylase; (1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate.
  
  
 0.844
otsA
Trehalose-6-phosphate synthase (Alpha,alpha-trehalose-phosphate synthase); Annotated from work of Cardoso et al, 2007 (PubMed 17185556) Molecular function: alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity.
 
  
 0.831
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.