| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carD | rbpA | PFREUD_18770 | PFREUD_10940 | Transcriptional regulator CarD; Probably regulates isp genes. | Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. | 0.961 |
| carD | rpoA | PFREUD_18770 | PFREUD_06070 | Transcriptional regulator CarD; Probably regulates isp genes. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.936 |
| carD | rpoB | PFREUD_18770 | PFREUD_05600 | Transcriptional regulator CarD; Probably regulates isp genes. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.943 |
| carD | rpoC | PFREUD_18770 | PFREUD_05610 | Transcriptional regulator CarD; Probably regulates isp genes. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.981 |
| carD | rpoZ | PFREUD_18770 | PFREUD_11420 | Transcriptional regulator CarD; Probably regulates isp genes. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.948 |
| gmk | mihF | PFREUD_11430 | PFREUD_11440 | Guanylate kinase, Guanosine monophosphate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Integration host factor MihF. | 0.881 |
| gmk | rpoB | PFREUD_11430 | PFREUD_05600 | Guanylate kinase, Guanosine monophosphate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.561 |
| gmk | rpoZ | PFREUD_11430 | PFREUD_11420 | Guanylate kinase, Guanosine monophosphate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.919 |
| mihF | gmk | PFREUD_11440 | PFREUD_11430 | Integration host factor MihF. | Guanylate kinase, Guanosine monophosphate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | 0.881 |
| mihF | rplJ | PFREUD_11440 | PFREUD_05570 | Integration host factor MihF. | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.928 |
| mihF | rpoA | PFREUD_11440 | PFREUD_06070 | Integration host factor MihF. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.922 |
| mihF | rpoB | PFREUD_11440 | PFREUD_05600 | Integration host factor MihF. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.897 |
| mihF | rpoC | PFREUD_11440 | PFREUD_05610 | Integration host factor MihF. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.811 |
| mihF | rpoZ | PFREUD_11440 | PFREUD_11420 | Integration host factor MihF. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.942 |
| mihF | rpsB | PFREUD_11440 | PFREUD_14780 | Integration host factor MihF. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.962 |
| mihF | rpsD | PFREUD_11440 | PFREUD_06060 | Integration host factor MihF. | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.962 |
| rbpA | carD | PFREUD_10940 | PFREUD_18770 | Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. | Transcriptional regulator CarD; Probably regulates isp genes. | 0.961 |
| rbpA | rpoA | PFREUD_10940 | PFREUD_06070 | Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.948 |
| rbpA | rpoB | PFREUD_10940 | PFREUD_05600 | Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.959 |
| rbpA | rpoC | PFREUD_10940 | PFREUD_05610 | Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.945 |