| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBL56696.1 | CBL56702.1 | PFREUD_11740 | PFREUD_11800 | GCN5-related N-acetyltransferase. | 5.2 Protein of unknown function similar to proteins from other organisms. | 0.415 |
| CBL56696.1 | hisA | PFREUD_11740 | PFREUD_11750 | GCN5-related N-acetyltransferase. | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)- 1-(5-phosphoribosyl)imidazole-4-carboxamide. | 0.804 |
| CBL56696.1 | hisB | PFREUD_11740 | PFREUD_11770 | GCN5-related N-acetyltransferase. | Imidazoleglycerol-phosphate dehydratase (IGPD). | 0.605 |
| CBL56696.1 | hisC | PFREUD_11740 | PFREUD_11780 | GCN5-related N-acetyltransferase. | Histidinol-phosphate aminotransferase (Imidazole acetol-phosphate transaminase); L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.605 |
| CBL56696.1 | hisD | PFREUD_11740 | PFREUD_11790 | GCN5-related N-acetyltransferase. | Histidinol dehydrogenase (HDH); Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.605 |
| CBL56696.1 | hisH | PFREUD_11740 | PFREUD_11760 | GCN5-related N-acetyltransferase. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.612 |
| CBL56702.1 | CBL56696.1 | PFREUD_11800 | PFREUD_11740 | 5.2 Protein of unknown function similar to proteins from other organisms. | GCN5-related N-acetyltransferase. | 0.415 |
| CBL56702.1 | hisA | PFREUD_11800 | PFREUD_11750 | 5.2 Protein of unknown function similar to proteins from other organisms. | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)- 1-(5-phosphoribosyl)imidazole-4-carboxamide. | 0.439 |
| CBL56702.1 | hisB | PFREUD_11800 | PFREUD_11770 | 5.2 Protein of unknown function similar to proteins from other organisms. | Imidazoleglycerol-phosphate dehydratase (IGPD). | 0.584 |
| CBL56702.1 | hisC | PFREUD_11800 | PFREUD_11780 | 5.2 Protein of unknown function similar to proteins from other organisms. | Histidinol-phosphate aminotransferase (Imidazole acetol-phosphate transaminase); L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.584 |
| CBL56702.1 | hisD | PFREUD_11800 | PFREUD_11790 | 5.2 Protein of unknown function similar to proteins from other organisms. | Histidinol dehydrogenase (HDH); Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.574 |
| CBL56702.1 | hisH | PFREUD_11800 | PFREUD_11760 | 5.2 Protein of unknown function similar to proteins from other organisms. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.573 |
| CBL56702.1 | ybaK/EbsC | PFREUD_11800 | PFREUD_11810 | 5.2 Protein of unknown function similar to proteins from other organisms. | YbaC/EbsC protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | 0.651 |
| hisA | CBL56696.1 | PFREUD_11750 | PFREUD_11740 | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)- 1-(5-phosphoribosyl)imidazole-4-carboxamide. | GCN5-related N-acetyltransferase. | 0.804 |
| hisA | CBL56702.1 | PFREUD_11750 | PFREUD_11800 | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)- 1-(5-phosphoribosyl)imidazole-4-carboxamide. | 5.2 Protein of unknown function similar to proteins from other organisms. | 0.439 |
| hisA | hisB | PFREUD_11750 | PFREUD_11770 | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)- 1-(5-phosphoribosyl)imidazole-4-carboxamide. | Imidazoleglycerol-phosphate dehydratase (IGPD). | 0.998 |
| hisA | hisC | PFREUD_11750 | PFREUD_11780 | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)- 1-(5-phosphoribosyl)imidazole-4-carboxamide. | Histidinol-phosphate aminotransferase (Imidazole acetol-phosphate transaminase); L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.986 |
| hisA | hisD | PFREUD_11750 | PFREUD_11790 | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)- 1-(5-phosphoribosyl)imidazole-4-carboxamide. | Histidinol dehydrogenase (HDH); Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.997 |
| hisA | hisH | PFREUD_11750 | PFREUD_11760 | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)- 1-(5-phosphoribosyl)imidazole-4-carboxamide. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.999 |
| hisA | ybaK/EbsC | PFREUD_11750 | PFREUD_11810 | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)- 1-(5-phosphoribosyl)imidazole-4-carboxamide. | YbaC/EbsC protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. | 0.502 |