STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gltBGlutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. (1502 aa)    
Predicted Functional Partners:
CBL55697.1
6 Protein of unknown function, without similarity to other proteins.
 
 0.999
gltD
Glutamate synthase small subunit; 2 L-Glutamate + NADP+ <=> L-Glutamine + 2-Oxoglutarate + NADPH + H+.
 0.999
gdh
Glutamate dehydrogenase (NAD(P)-glutamate dehydrogenase); L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH. Homohexamer (By similarity). Belongs to the Glu/Leu/Phe/Val dehydrogenases family. Evidenced as a heat stress proetin in P. freudenreichii.
  
 0.999
guaB2
Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase.
  
 
 0.992
CBL57095.1
Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis.
  
 
 0.990
glnA
Glutamine synthetase; # ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine; Belongs to the glutamine synthetase family.
  
 
 0.990
carB
Carbamoyl-phosphate synthase large chain (Carbamoyl-phosphate synthetase ammonia chain); 2 ATP + L-glutamine + HCO3- + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate; Binds 3 manganese ions per subunit; Belongs to the CarB family.
  
 
 0.987
glmS
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 0.968
gadB
L-Glutamate <=> 4-Aminobutanoate + CO2 L-Aspartate <=> beta-Alanine + CO2; Belongs to the group II decarboxylase family.
    
 0.963
gcvP
Glycine dehydrogenase [decarboxylating] (Glycine decarboxylase) (Glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 0.954
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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