STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBL56889.1BioY family protein. Membrane protein; BioY family. A number of bacterial genes are involved in bioconversion of pimelate into dethiobiotin. BioY is involved in this process, however the exact function of the protein is unknown. (209 aa)    
Predicted Functional Partners:
CBL56886.1
Cobalt permease.
 
 0.995
CBL56888.1
ABC-type transporter, ATPase component.
 
 
 0.995
CBL56146.1
ABC transporter-associated permease.
  
 0.921
cbiQ1
ABC-type transporter, permease components (ABC-type cobalt transport system, permease component CbiQ).
  
 0.921
cbiA
Cobyrinic acid A,C-diamide synthase, CbiA; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
    0.645
cbiO1
Cobalt import ATP-binding protein CbiO; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
   
 
 0.643
cbiO3
ABC transporter, ATP-binding protein; Locus ABC transporter PF #2140, 2141 et 2475.
   
 
 0.643
cbiQ2
Cobalt transport protein CbiQ.
  
 
 0.622
pf2694
ABC-type transporter, permease components.
   
 
 0.595
birA
BirA, Biotin-(acetyl-CoA carboxylase) ligase; Biotin is covalently attached at the active site of certain enzymes that transfer carbon dioxide from bicarbonate to organic acids to form cellular metabolites. ATP + Biotin + Apo-[acetyl-CoA:carbon-dioxide ligase (ADP-forming)] <=> AMP + Pyrophosphate + [Acetyl-CoA:carbon-dioxide ligase (ADP-forming)].
 
   
 0.566
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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