STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gabAldehyde dehydrogenase (Succinate-semialdehyde dehydrogenase) (NAD-dependent aldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family. (488 aa)    
Predicted Functional Partners:
gabT
4-aminobutyrate aminotransferase; 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde +; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.937
CBL57694.1
Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.937
sdhA
# Succinate + FAD <=> FADH2 + Fumarate, A flavoprotein (FAD) containing iron-sulfur centres. A component of EC 1.3.5.1 succinate dehydrogenase (ubiquinone).
   
 0.923
sdhA3
Succinate dehydrogenase flavoprotein subunit; Succinate + FAD <=> FADH2 + Fumarate.
   
 0.923
sdhB
Succinate dehydrogenase, subunit B; # Succinate + FAD <=> FADH2 + Fumarate.
   
 
 0.909
sdhB3
Succinate + acceptor <=> fumarate + reduced acceptor.
   
 
 0.909
cat
Coenzyme A transferase (Putative succinyl-CoA or butyryl-CoA:coenzyme A transferase); acyl-CoA + acetate = a fatty acid anion + acetyl-CoA OR: succinate + acetyl-CoA = succinyl-CoA + acetate OR (in Pf): succinate + propionyl-CoA = succinyl-CoA + propionate.
  
 
 0.908
sdhC1
Succinate + FAD <=> FADH2 + Fumarate and Succinate + Acceptor <=> Fumarate + Reduced acceptor.
   
 
  0.900
sdhC2
Succinate dehydrogenase cytochrome B-558 subunit; Succinate + Acceptor <=> Fumarate + Reduced acceptor.
   
 
  0.900
odhA
2-oxoglutarate dehydrogenase, E1 and E2 components; Annotated from high similarity with Swiss-Prot entry Q8NRC3, a bifunctional enzyme of Corynebacterium glutamicum with E1 and E2 activity. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
  
 0.879
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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