| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBL57055.1 | ftsI | PFREUD_15570 | PFREUD_15560 | 6 Protein of unknown function, without similarity to other proteins. | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | 0.919 |
| CBL57055.1 | mraW | PFREUD_15570 | PFREUD_15580 | 6 Protein of unknown function, without similarity to other proteins. | S-adenosyl-L-methionine-dependent methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.857 |
| CBL57055.1 | mraZ | PFREUD_15570 | PFREUD_15590 | 6 Protein of unknown function, without similarity to other proteins. | Protein mraZ; Belongs to the mra (murein region A) gene cluster, involved in cell wall biosynthesis and cell division. | 0.635 |
| CBL57055.1 | murD | PFREUD_15570 | PFREUD_15520 | 6 Protein of unknown function, without similarity to other proteins. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.677 |
| CBL57055.1 | murE | PFREUD_15570 | PFREUD_15550 | 6 Protein of unknown function, without similarity to other proteins. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.621 |
| CBL57055.1 | murF | PFREUD_15570 | PFREUD_15540 | 6 Protein of unknown function, without similarity to other proteins. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.621 |
| CBL57055.1 | murG | PFREUD_15570 | PFREUD_15500 | 6 Protein of unknown function, without similarity to other proteins. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.480 |
| ftsI | CBL57055.1 | PFREUD_15560 | PFREUD_15570 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | 6 Protein of unknown function, without similarity to other proteins. | 0.919 |
| ftsI | mraW | PFREUD_15560 | PFREUD_15580 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | S-adenosyl-L-methionine-dependent methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.853 |
| ftsI | mraZ | PFREUD_15560 | PFREUD_15590 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | Protein mraZ; Belongs to the mra (murein region A) gene cluster, involved in cell wall biosynthesis and cell division. | 0.638 |
| ftsI | murD | PFREUD_15560 | PFREUD_15520 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.958 |
| ftsI | murE | PFREUD_15560 | PFREUD_15550 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.975 |
| ftsI | murF | PFREUD_15560 | PFREUD_15540 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.974 |
| ftsI | murG | PFREUD_15560 | PFREUD_15500 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.971 |
| mraW | CBL57055.1 | PFREUD_15580 | PFREUD_15570 | S-adenosyl-L-methionine-dependent methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 6 Protein of unknown function, without similarity to other proteins. | 0.857 |
| mraW | ftsI | PFREUD_15580 | PFREUD_15560 | S-adenosyl-L-methionine-dependent methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | 0.853 |
| mraW | mraZ | PFREUD_15580 | PFREUD_15590 | S-adenosyl-L-methionine-dependent methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | Protein mraZ; Belongs to the mra (murein region A) gene cluster, involved in cell wall biosynthesis and cell division. | 0.989 |
| mraW | murD | PFREUD_15580 | PFREUD_15520 | S-adenosyl-L-methionine-dependent methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.735 |
| mraW | murE | PFREUD_15580 | PFREUD_15550 | S-adenosyl-L-methionine-dependent methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.775 |
| mraW | murF | PFREUD_15580 | PFREUD_15540 | S-adenosyl-L-methionine-dependent methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.746 |