| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBL57055.1 | ftsI | PFREUD_15570 | PFREUD_15560 | 6 Protein of unknown function, without similarity to other proteins. | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | 0.898 |
| CBL57055.1 | mraW | PFREUD_15570 | PFREUD_15580 | 6 Protein of unknown function, without similarity to other proteins. | S-adenosyl-L-methionine-dependent methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.898 |
| CBL57055.1 | mraY | PFREUD_15570 | PFREUD_15530 | 6 Protein of unknown function, without similarity to other proteins. | Phospho-N-acetylmuramoyl-pentapeptide- transferase (UDP-MurNAc-pentapeptide phosphotransferase); First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.625 |
| CBL57055.1 | mraZ | PFREUD_15570 | PFREUD_15590 | 6 Protein of unknown function, without similarity to other proteins. | Protein mraZ; Belongs to the mra (murein region A) gene cluster, involved in cell wall biosynthesis and cell division. | 0.771 |
| CBL57055.1 | murD | PFREUD_15570 | PFREUD_15520 | 6 Protein of unknown function, without similarity to other proteins. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.684 |
| CBL57055.1 | murE | PFREUD_15570 | PFREUD_15550 | 6 Protein of unknown function, without similarity to other proteins. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.633 |
| CBL57055.1 | murF | PFREUD_15570 | PFREUD_15540 | 6 Protein of unknown function, without similarity to other proteins. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.638 |
| CBL57055.1 | murG | PFREUD_15570 | PFREUD_15500 | 6 Protein of unknown function, without similarity to other proteins. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.463 |
| ftsI | CBL57055.1 | PFREUD_15560 | PFREUD_15570 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | 6 Protein of unknown function, without similarity to other proteins. | 0.898 |
| ftsI | mraW | PFREUD_15560 | PFREUD_15580 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | S-adenosyl-L-methionine-dependent methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.870 |
| ftsI | mraY | PFREUD_15560 | PFREUD_15530 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | Phospho-N-acetylmuramoyl-pentapeptide- transferase (UDP-MurNAc-pentapeptide phosphotransferase); First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.947 |
| ftsI | mraZ | PFREUD_15560 | PFREUD_15590 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | Protein mraZ; Belongs to the mra (murein region A) gene cluster, involved in cell wall biosynthesis and cell division. | 0.617 |
| ftsI | murD | PFREUD_15560 | PFREUD_15520 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.961 |
| ftsI | murE | PFREUD_15560 | PFREUD_15550 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.979 |
| ftsI | murF | PFREUD_15560 | PFREUD_15540 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.974 |
| ftsI | murG | PFREUD_15560 | PFREUD_15500 | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.938 |
| mraW | CBL57055.1 | PFREUD_15580 | PFREUD_15570 | S-adenosyl-L-methionine-dependent methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 6 Protein of unknown function, without similarity to other proteins. | 0.898 |
| mraW | ftsI | PFREUD_15580 | PFREUD_15560 | S-adenosyl-L-methionine-dependent methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | Cell division protein FtsI (penicillin-binding protein 2) (Peptidoglycan glycosyltransferase); Transpeptidase activity involved in the biosynthesis of septal peptidoglycan. | 0.870 |
| mraW | mraY | PFREUD_15580 | PFREUD_15530 | S-adenosyl-L-methionine-dependent methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | Phospho-N-acetylmuramoyl-pentapeptide- transferase (UDP-MurNAc-pentapeptide phosphotransferase); First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.667 |
| mraW | mraZ | PFREUD_15580 | PFREUD_15590 | S-adenosyl-L-methionine-dependent methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | Protein mraZ; Belongs to the mra (murein region A) gene cluster, involved in cell wall biosynthesis and cell division. | 0.992 |
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