Indole-3-glycerol phosphate synthase (TrpC); 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O; Belongs to the TrpC family.

Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]

Tryptophan synthase alpha chain (TrpA); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.

Tryptophan synthase beta chain (TrpB); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.

Para-aminobenzoate synthase.

1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)- 1-(5-phosphoribosyl)imidazole-4-carboxamide.

Response regulator receiver protein.

Chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.

Prephenate dehydratase; L-Arogenate <=> L-Phenylalanine + H2O + CO2 and Prephenate <=> Phenylpyruvate + H2O + CO2.