| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBL57106.1 | pepP | PFREUD_16080 | PFREUD_16090 | 5.2 Protein of unknown function similar to proteins from other organisms. | Xaa-Pro aminopeptidase I; Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Binds 2 manganese ions per subunit.Belongs to the peptidase M24B family. | 0.554 |
| CBL57352.1 | pepP | PFREUD_18600 | PFREUD_16090 | 5.2 Protein of unknown function similar to proteins from other organisms. | Xaa-Pro aminopeptidase I; Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Binds 2 manganese ions per subunit.Belongs to the peptidase M24B family. | 0.425 |
| guaB1 | guaB2 | PFREUD_06480 | PFREUD_06490 | Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase. | 0.975 |
| guaB1 | nifJ1 | PFREUD_06480 | PFREUD_01840 | Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase, Pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin. | 0.551 |
| guaB1 | nifJ2 | PFREUD_06480 | PFREUD_07070 | Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Pyruvate:ferredoxin (Flavodoxin) oxidoreductase. | 0.596 |
| guaB1 | pepP | PFREUD_06480 | PFREUD_16090 | Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Xaa-Pro aminopeptidase I; Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Binds 2 manganese ions per subunit.Belongs to the peptidase M24B family. | 0.486 |
| guaB2 | guaB1 | PFREUD_06490 | PFREUD_06480 | Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase. | Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.975 |
| guaB2 | nifJ1 | PFREUD_06490 | PFREUD_01840 | Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase. | Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase, Pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin. | 0.618 |
| guaB2 | nifJ2 | PFREUD_06490 | PFREUD_07070 | Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase. | Pyruvate:ferredoxin (Flavodoxin) oxidoreductase. | 0.623 |
| guaB2 | pepP | PFREUD_06490 | PFREUD_16090 | Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase. | Xaa-Pro aminopeptidase I; Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Binds 2 manganese ions per subunit.Belongs to the peptidase M24B family. | 0.503 |
| hisS | pepP | PFREUD_11620 | PFREUD_16090 | Histidyl-tRNA synthetase (Histidine--tRNA ligase) (HisRS). | Xaa-Pro aminopeptidase I; Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Binds 2 manganese ions per subunit.Belongs to the peptidase M24B family. | 0.405 |
| nifJ1 | guaB1 | PFREUD_01840 | PFREUD_06480 | Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase, Pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin. | Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.551 |
| nifJ1 | guaB2 | PFREUD_01840 | PFREUD_06490 | Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase, Pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin. | Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase. | 0.618 |
| nifJ1 | nifJ2 | PFREUD_01840 | PFREUD_07070 | Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase, Pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin. | Pyruvate:ferredoxin (Flavodoxin) oxidoreductase. | 0.999 |
| nifJ1 | pepP | PFREUD_01840 | PFREUD_16090 | Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase, Pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin. | Xaa-Pro aminopeptidase I; Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Binds 2 manganese ions per subunit.Belongs to the peptidase M24B family. | 0.557 |
| nifJ2 | guaB1 | PFREUD_07070 | PFREUD_06480 | Pyruvate:ferredoxin (Flavodoxin) oxidoreductase. | Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.596 |
| nifJ2 | guaB2 | PFREUD_07070 | PFREUD_06490 | Pyruvate:ferredoxin (Flavodoxin) oxidoreductase. | Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) / GMP reductase. | 0.623 |
| nifJ2 | nifJ1 | PFREUD_07070 | PFREUD_01840 | Pyruvate:ferredoxin (Flavodoxin) oxidoreductase. | Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase, Pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin. | 0.999 |
| nifJ2 | pepP | PFREUD_07070 | PFREUD_16090 | Pyruvate:ferredoxin (Flavodoxin) oxidoreductase. | Xaa-Pro aminopeptidase I; Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Binds 2 manganese ions per subunit.Belongs to the peptidase M24B family. | 0.554 |
| pepN | pepP | PFREUD_08100 | PFREUD_16090 | Aminopeptidase with broad substrate specificity. Preference for leucine, cleaves also next to Arg and lysine. Release of an N-terminal aa, Xaa-|-Yaa-. Xaa is preferably Ala. Xaa-Pro may be released. Peptidase M1 family. Monomer. Binds 1 zinc ion per subunit, Cytoplasmic. | Xaa-Pro aminopeptidase I; Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Binds 2 manganese ions per subunit.Belongs to the peptidase M24B family. | 0.545 |