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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
citECitrate lyase beta chain (Citrase beta chain) (Citrate(Pro-3S)-lyase beta chain); Citrate <=> Acetate + Oxaloacetate / (3S)-Citryl-CoA <=> Acetyl-CoA + Oxaloacetate; Belongs to the HpcH/HpaI aldolase family. (287 aa)    
Predicted Functional Partners:
araD1
L-ribulokinase (ribulokinase); ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate. L-arabinose catabolism; second step. Transcription is repressed by glucose and by the binding of araR to the operon promoter. L-arabinose acts as an inducer by inhibiting the binding of araR to the DNA, thus allowing expression of the gene. Belongs to the ribulokinase family.
   
    0.732
araD
L-ribulose-5-phosphate 4-epimerase AraD; L-Ribulose 5-phosphate <=> D-Xylulose 5-phosphate.
   
    0.732
purD
Phosphoribosylamine-glycine ligase; ATP + 5-Phosphoribosylamine + Glycine <=> ADP + Orthophosphate + 5prime-Phosphoribosylglycinamide; Belongs to the GARS family.
     
 0.654
CBL56461.1
5.2 Protein of unknown function similar to proteins from other organisms.
      
 0.645
mgtE
Magnesium (Mg2+) transporter.
       0.611
CBL57111.1
5.2 Protein of unknown function similar to proteins from other organisms.
       0.611
CBL57108.1
5.2 Protein of unknown function similar to proteins from other organisms.
  
    0.541
mutB
Methylmalonyl-CoA mutase catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates. Induced by heat and acid stresses.
  
  
 0.530
nifJ2
Pyruvate:ferredoxin (Flavodoxin) oxidoreductase.
     
 0.464
nifJ1
Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase, Pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin.
     
 0.437
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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