STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fdxAFerredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (106 aa)    
Predicted Functional Partners:
nifJ1
Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase, Pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin.
  
  
 0.983
nifJ2
Pyruvate:ferredoxin (Flavodoxin) oxidoreductase.
  
  
 0.969
CBL57125.1
Aminotransferase; Molecular function: transaminase activity.
    
 0.951
CBL56066.1
Pyruvate flavodoxin/ferredoxin oxidoreductase.
  
  
 0.735
dus
TIM-barrel enzyme, dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
   
    0.603
CBL55697.1
6 Protein of unknown function, without similarity to other proteins.
  
 
 0.597
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
    0.561
ldh1
L-Lactate dehydrogenase; (S)-Lactate + NAD+ <=> Pyruvate + NADH + H+; Belongs to the LDH/MDH superfamily.
  
    0.561
ldh2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
    0.561
gya
Glycolate + NAD+ = glyoxylate + NADH. _ Glycolate + NAD+ <=> Glyoxylate + NADH + H+; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.466
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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