STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aspA1Aspartate ammonia-lyase (Aspartase); L-aspartate = fumarate + NH3. (489 aa)    
Predicted Functional Partners:
ansA
L-asparagine + H2O = L-aspartate + NH3.
  
 
 0.948
nadB1
L-aspartate oxidase (LASPO) (Quinolinate synthetase B); Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
   
 0.944
aspA2
L-Aspartate <=> Fumarate + NH3.
 
  
0.937
nadB2
L-aspartate oxidase (LASPO) (Quinolinate synthetase B).
     
 0.933
argH
Argininosuccinate lyase (Arginosuccinase); N-(L-Arginino)succinate <=> Fumarate + L-Arginine.
     
 0.931
purA
Adenylosuccinate synthetase (IMP--aspartate ligase) (AdSS) (AMPSase); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.915
purB
Adenylosuccinate lyase; N6-(1,2-Dicarboxyethyl)-AMP <=> Fumarate + AMP 1-(5prime-Phosphoribosyl)-5-amino-4-(N- succinocarboxamide)-imidazole These proteins are active as tetramers. The four active sites of the homotetrameric enzyme are each formed by residues from three different subunits; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.901
pyrB
Carbamoyl phosphate + L-Aspartate <=> Orthophosphate + N-Carbamoyl-L-aspartate; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
     
  0.900
asnB
Asparagine synthase (Glutamine-hydrolyzing); ATP + L-Aspartate + L-Glutamine + H2O <=> AMP + Pyrophosphate + L-Asparagine + L-Glutamate.
     
  0.900
dcuA
C4-dicarboxylate transporter.
 
  
 0.879
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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