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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBL57284.1Two-component system, regulatory protein. (219 aa)    
Predicted Functional Partners:
CBL57285.1
Sensor kinase-Membrane protein.
 
 
 0.964
CBL57299.1
Two-component system sensor kinase. Membrane protein.
 
 
 0.861
CBL57699.1
Two component sensor kinase.
 
 0.858
CBL55679.1
Two component sensor kinase.
 
 0.855
CBL57020.1
Signal transduction histidine kinase/two-component system sensor kinase.
 
 
 0.838
CBL56203.1
Two-component system sensor kinase.
 
 
 0.612
CBL55532.1
Two-component system sensor kinase.
 
 
 0.592
CBL57286.1
Hypothetical membrane protein.
       0.523
CBL57283.1
6 Protein of unknown function, without similarity to other proteins.
       0.468
CBL55659.1
ATP-binding region, ATPase-like:Histidine kinase, Histidine kinase A-like precursor; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
 
   0.408
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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