Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CBL57319.15.2 Protein of unknown function similar to proteins from other organisms. (119 aa)    
Predicted Functional Partners:
pf1655
Carboxylic ester hydrolase; Recombinant protein active on 1- naphthyl actetate and 1- naphthyl propionate.
 
     0.888
CBL57317.1
Isochorismatase hydrolase; An enzyme that catalyzes the conversion of isochorismate to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of the vinyl ether bond.Isochorismatase is part of the phenazine biosynthesis pathway. Phenazines are antimicrobial compounds that provide the competitive advantage for certain bacteria.
 
     0.878
CBL57320.1
6 Protein of unknown function, without similarity to other proteins.
       0.773
CBL56774.1
5.2 Protein of unknown function similar to proteins from other organisms.
  
     0.772
CBL55845.1
Isochorismatase hydrolase; Young IG, Gibson F. Biochim. Biophys. Acta. 177 (1969) 401-11. Isochorismate + H2O <=> 2,3-Dihydro-2,3-dihydroxybenzoate + Pyruvate.
  
     0.691
CBL57913.1
Oxidoreductase.
  
     0.609
vanZ
VanZ; Confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te)Arthur M, Depardieu F, Molinas C, Reynolds P, Courvalin P; , Gene 1995;154:87-92.: The vanZ gene of Tn1546 from Enterococcus faecium BM4147 confers resistance to teicoplanin.
  
     0.487
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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