| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBL55584.1 | CBL55659.1 | PFREUD_00810 | PFREUD_01410 | Sensor protein, ATPase-like:Histidine kinase; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | ATP-binding region, ATPase-like:Histidine kinase, Histidine kinase A-like precursor; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | 0.740 |
| CBL55584.1 | CBL55857.1 | PFREUD_00810 | PFREUD_03260 | Sensor protein, ATPase-like:Histidine kinase; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | Sensor protein; Two component system regulator. | 0.745 |
| CBL55584.1 | phoU | PFREUD_00810 | PFREUD_18800 | Sensor protein, ATPase-like:Histidine kinase; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | Putative phosphate transport system protein; Plays a role in the regulation of phosphate uptake. | 0.429 |
| CBL55584.1 | regX | PFREUD_00810 | PFREUD_18780 | Sensor protein, ATPase-like:Histidine kinase; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | Response regulator receiver; Probably forms part of a two-component regulatory system regX3/senX3. | 0.879 |
| CBL55584.1 | senX | PFREUD_00810 | PFREUD_18790 | Sensor protein, ATPase-like:Histidine kinase; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | Sensor-like histidine kinase; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | 0.749 |
| CBL55659.1 | CBL55584.1 | PFREUD_01410 | PFREUD_00810 | ATP-binding region, ATPase-like:Histidine kinase, Histidine kinase A-like precursor; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | Sensor protein, ATPase-like:Histidine kinase; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | 0.740 |
| CBL55659.1 | regX | PFREUD_01410 | PFREUD_18780 | ATP-binding region, ATPase-like:Histidine kinase, Histidine kinase A-like precursor; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | Response regulator receiver; Probably forms part of a two-component regulatory system regX3/senX3. | 0.883 |
| CBL55857.1 | CBL55584.1 | PFREUD_03260 | PFREUD_00810 | Sensor protein; Two component system regulator. | Sensor protein, ATPase-like:Histidine kinase; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | 0.745 |
| CBL55857.1 | regX | PFREUD_03260 | PFREUD_18780 | Sensor protein; Two component system regulator. | Response regulator receiver; Probably forms part of a two-component regulatory system regX3/senX3. | 0.884 |
| carD | phoU | PFREUD_18770 | PFREUD_18800 | Transcriptional regulator CarD; Probably regulates isp genes. | Putative phosphate transport system protein; Plays a role in the regulation of phosphate uptake. | 0.507 |
| carD | regX | PFREUD_18770 | PFREUD_18780 | Transcriptional regulator CarD; Probably regulates isp genes. | Response regulator receiver; Probably forms part of a two-component regulatory system regX3/senX3. | 0.502 |
| carD | senX | PFREUD_18770 | PFREUD_18790 | Transcriptional regulator CarD; Probably regulates isp genes. | Sensor-like histidine kinase; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | 0.523 |
| coaD | regX | PFREUD_14480 | PFREUD_18780 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Response regulator receiver; Probably forms part of a two-component regulatory system regX3/senX3. | 0.414 |
| nuoG | regX | PFREUD_05220 | PFREUD_18780 | NADH-quinone oxidoreductase chain G (NADH dehydrogenase I, chain G); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. | Response regulator receiver; Probably forms part of a two-component regulatory system regX3/senX3. | 0.442 |
| phoU | CBL55584.1 | PFREUD_18800 | PFREUD_00810 | Putative phosphate transport system protein; Plays a role in the regulation of phosphate uptake. | Sensor protein, ATPase-like:Histidine kinase; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | 0.429 |
| phoU | carD | PFREUD_18800 | PFREUD_18770 | Putative phosphate transport system protein; Plays a role in the regulation of phosphate uptake. | Transcriptional regulator CarD; Probably regulates isp genes. | 0.507 |
| phoU | regX | PFREUD_18800 | PFREUD_18780 | Putative phosphate transport system protein; Plays a role in the regulation of phosphate uptake. | Response regulator receiver; Probably forms part of a two-component regulatory system regX3/senX3. | 0.618 |
| phoU | senX | PFREUD_18800 | PFREUD_18790 | Putative phosphate transport system protein; Plays a role in the regulation of phosphate uptake. | Sensor-like histidine kinase; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | 0.677 |
| recG | regX | PFREUD_14510 | PFREUD_18780 | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3prime to 5prime polarity. RecG unwind branched duplex DNA (Y-DNA). | Response regulator receiver; Probably forms part of a two-component regulatory system regX3/senX3. | 0.436 |
| regX | CBL55584.1 | PFREUD_18780 | PFREUD_00810 | Response regulator receiver; Probably forms part of a two-component regulatory system regX3/senX3. | Sensor protein, ATPase-like:Histidine kinase; ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. | 0.879 |