STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iolD3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing); Carbohydrate degradation, myo-inositol degradation to acetyl-CoA; Belongs to the TPP enzyme family. (635 aa)    
Predicted Functional Partners:
iolB
iolB (Myo-inositol catabolism IolB protein); Carbohydrate degradation, myo-inositol degradation to acetyl-CoA.
 
 
 0.999
iolE
IolE (Myo-inositol catabolism IolAEprotein) (Inosose dehydratase) (2-keto-myo-inositol dehydratase); Carbohydrate degradation, myo-inositol degradation to acetyl-CoA.
 
 
 0.992
iolC
iolC (Myo-inositol catabolism iolC protein); Carbohydrate degradation, myo-inositol degradation to acetyl-CoA.
 
  
 0.968
iolG1
iolG1 (Myo-inositol catabolism IolG1 protein) (myo-inositol 2-dehydrogenase); Carbohydrate degradation, myo-inositol degradation to acetyl-CoA.
 
  
 0.952
CBL57399.1
5.2 Protein of unknown function similar to proteins from other organisms.
 
    0.898
iolH
iolG2 (Myo-inositol catabolism IolG2 protein) (Inositol 2-dehydrogenase); Inositol + NAD+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADH + H+.
 
  
 0.889
iolA
iolA (Myo-inositol catabolism IolA protein) (Methylmalonic acid semialdehyde dehydrogenase); * 3-Oxopropanoate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+.
  
 0.844
iol
myo-Inositol + NAD+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADH + H+.
 
  
 0.832
CBL57834.1
myo-Inositol + NAD+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADH + H+.
 
  
 0.829
CBL57397.1
GntR-family protein transcriptional regulator.
 
  
 0.770
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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