STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbiO3ABC transporter, ATP-binding protein; Locus ABC transporter PF #2140, 2141 et 2475. (556 aa)    
Predicted Functional Partners:
cbiQ1
ABC-type transporter, permease components (ABC-type cobalt transport system, permease component CbiQ).
 
 0.998
CBL57511.1
ABC transporter.
 
    0.938
CBL57514.1
Cobalt ABC transporter; Chorismate + NH3 <=> Anthranilate + Pyruvate + H2O.
 
    0.842
cbiE
Precorrin methylase (precorrin-3B C17-methyltransferase) CbiE/G/H fusion protein; S-Adenosyl-L-methionine + Precorrin 3B <=> S-Adenosyl-L-homocysteine + Precorrin 4 / Cobalt-precorrin 3 + S-Adenosyl-L-methionine <=> Cobalt-precorrin 4 + S-Adenosyl-L-homocysteine.
  
  
 0.753
CBL56886.1
Cobalt permease.
 
 
 0.685
cbiQ2
Cobalt transport protein CbiQ.
  
 
 0.677
CBL56889.1
BioY family protein. Membrane protein; BioY family. A number of bacterial genes are involved in bioconversion of pimelate into dethiobiotin. BioY is involved in this process, however the exact function of the protein is unknown.
   
 
 0.643
CBL56146.1
ABC transporter-associated permease.
  
 
 0.641
cbiM
Cobalt transport protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
 
 0.608
hemD
Uroporphyrinogen-III synthase HemD; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
     
 0.500
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
Server load: low (12%) [HD]