STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadB2L-aspartate oxidase (LASPO) (Quinolinate synthetase B). (529 aa)    
Predicted Functional Partners:
nadA
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 0.997
nadC
Nicotinate-nucleotide pyrophosphorylase (carboxylating); Nicotinate D-ribonucleotide + Pyrophosphate + CO2 <=> Pyridine-2,3-dicarboxylate + 5-Phospho-alpha-D-ribose 1-diphosphate; Belongs to the NadC/ModD family.
  
 0.978
argG
Argininosuccinate synthase; ATP + L-Citrulline + L-Aspartate <=> AMP + Pyrophosphate + N-(L-Arginino)succinate; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
     
 0.964
purA
Adenylosuccinate synthetase (IMP--aspartate ligase) (AdSS) (AMPSase); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.934
aspA1
Aspartate ammonia-lyase (Aspartase); L-aspartate = fumarate + NH3.
     
 0.933
aspA2
L-Aspartate <=> Fumarate + NH3.
     
 0.933
nadB1
L-aspartate oxidase (LASPO) (Quinolinate synthetase B); Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
  
 
0.923
ansA
L-asparagine + H2O = L-aspartate + NH3.
   
 
 0.909
pyrB
Carbamoyl phosphate + L-Aspartate <=> Orthophosphate + N-Carbamoyl-L-aspartate; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
     
  0.900
asnB
Asparagine synthase (Glutamine-hydrolyzing); ATP + L-Aspartate + L-Glutamine + H2O <=> AMP + Pyrophosphate + L-Asparagine + L-Glutamate.
     
  0.900
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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