STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBL57694.1Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)    
Predicted Functional Partners:
gadB
L-Glutamate <=> 4-Aminobutanoate + CO2 L-Aspartate <=> beta-Alanine + CO2; Belongs to the group II decarboxylase family.
  
 0.942
gab
Aldehyde dehydrogenase (Succinate-semialdehyde dehydrogenase) (NAD-dependent aldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family.
 
 0.937
iolA
iolA (Myo-inositol catabolism IolA protein) (Methylmalonic acid semialdehyde dehydrogenase); * 3-Oxopropanoate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+.
 
 0.937
aldB
(S)-lactaldehyde + NAD(+) + H(2)O <=> (S)-lactate + NADH; Belongs to the aldehyde dehydrogenase family.
 
 0.937
gabT
4-aminobutyrate aminotransferase; 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde +; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.918
CBL57693.1
Hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
 0.830
adh
Alcohol dehydrogenase.
  
 
 0.819
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
      
 0.672
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
      
 0.666
pta
Acetyl-CoA + Orthophosphate <=> CoA + Acetyl phosphate / Propanoyl-CoA + Orthophosphate <=> Propanoyl phosphate + CoA.
     
 0.662
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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