| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBL55691.1 | uvrA4 | PFREUD_01760 | PFREUD_22340 | Peptidase; Pfam domain. | Excinuclease ATPase subunit UvrA. | 0.401 |
| CBL57738.1 | uvrA4 | PFREUD_22350 | PFREUD_22340 | Zinc finger protein; This family of domains are likely to bind to zinc ions. They contain many conserved cysteine and histidine residues. | Excinuclease ATPase subunit UvrA. | 0.509 |
| gltB | recA | PFREUD_11860 | PFREUD_13130 | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | RecA (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.746 |
| gltB | uvrA4 | PFREUD_11860 | PFREUD_22340 | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | Excinuclease ATPase subunit UvrA. | 0.480 |
| mfd | uvrA4 | PFREUD_17350 | PFREUD_22340 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Excinuclease ATPase subunit UvrA. | 0.633 |
| mfd | uvrC | PFREUD_17350 | PFREUD_15200 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | UvrABC system protein C (Protein uvrC) (Excinuclease ABC subunit C); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.530 |
| pcrA | recA | PFREUD_06800 | PFREUD_13130 | ATP-dependent DNA helicase. | RecA (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.738 |
| pcrA | uvrA4 | PFREUD_06800 | PFREUD_22340 | ATP-dependent DNA helicase. | Excinuclease ATPase subunit UvrA. | 0.467 |
| pcrA | uvrB | PFREUD_06800 | PFREUD_15300 | ATP-dependent DNA helicase. | UvrABC system protein B (Protein uvrB) (Excinuclease ABC subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesi [...] | 0.877 |
| pcrA | uvrC | PFREUD_06800 | PFREUD_15200 | ATP-dependent DNA helicase. | UvrABC system protein C (Protein uvrC) (Excinuclease ABC subunit C); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.773 |
| pcrA | uvrD | PFREUD_06800 | PFREUD_09880 | ATP-dependent DNA helicase. | DNA helicase. | 0.965 |
| recA | gltB | PFREUD_13130 | PFREUD_11860 | RecA (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | 0.746 |
| recA | pcrA | PFREUD_13130 | PFREUD_06800 | RecA (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | ATP-dependent DNA helicase. | 0.738 |
| recA | uvrA4 | PFREUD_13130 | PFREUD_22340 | RecA (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | Excinuclease ATPase subunit UvrA. | 0.478 |
| recA | uvrB | PFREUD_13130 | PFREUD_15300 | RecA (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | UvrABC system protein B (Protein uvrB) (Excinuclease ABC subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesi [...] | 0.813 |
| recA | uvrC | PFREUD_13130 | PFREUD_15200 | RecA (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | UvrABC system protein C (Protein uvrC) (Excinuclease ABC subunit C); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.565 |
| recA | uvrD | PFREUD_13130 | PFREUD_09880 | RecA (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | DNA helicase. | 0.990 |
| uvrA4 | CBL55691.1 | PFREUD_22340 | PFREUD_01760 | Excinuclease ATPase subunit UvrA. | Peptidase; Pfam domain. | 0.401 |
| uvrA4 | CBL57738.1 | PFREUD_22340 | PFREUD_22350 | Excinuclease ATPase subunit UvrA. | Zinc finger protein; This family of domains are likely to bind to zinc ions. They contain many conserved cysteine and histidine residues. | 0.509 |
| uvrA4 | gltB | PFREUD_22340 | PFREUD_11860 | Excinuclease ATPase subunit UvrA. | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | 0.480 |
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