STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacI3The LacI family of proteins consist of transcriptional regulators related to the lac repressor. In this case, generally the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain. (344 aa)    
Predicted Functional Partners:
pptE
Phosphoenolpyruvate-protein phosphoryltransferase PptE; Belongs to the PEP-utilizing enzyme family.
   
 
 0.873
gltB
Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin.
    
 
 0.804
iolH
iolG2 (Myo-inositol catabolism IolG2 protein) (Inositol 2-dehydrogenase); Inositol + NAD+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADH + H+.
  
    0.473
CBL56195.1
ATP binding protein of ABC transporter, ATPase component; Molecular function: ATP binding. Responsible for energy coupling to the transport system.
 
  
 0.459
CBL56198.1
Probable ABC transporter permease protein for sugars; Locus abc transport; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.457
CBL57441.1
Phosphocarrier, HPr family; HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation across the cell membrane.
   
 
 0.453
deoR3
Putative regulatory protein, DeoR family; Transcription regulation of arabinose/xylulose/ribulose operon ?.
  
   
 0.451
ytfT
Ribose transport system permease protein RbsC, Putative ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.439
biaA
Locus abc transport.
 
  
 0.433
deoR1
Transcriptional regulator of sugar metabolism.
  
   
 0.426
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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