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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacI4Transcriptional regulator, LacI family (HTH-type transcriptional regulator degA). (347 aa)    
Predicted Functional Partners:
pptE
Phosphoenolpyruvate-protein phosphoryltransferase PptE; Belongs to the PEP-utilizing enzyme family.
   
 
 0.873
gltB
Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin.
    
 
 0.804
sseB
Thiosulfate + Cyanide <=> Sulfite + Thiocyanate.
       0.693
CBL57834.1
myo-Inositol + NAD+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADH + H+.
 
     0.613
CBL57441.1
Phosphocarrier, HPr family; HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation across the cell membrane.
   
 
 0.453
CBL56195.1
ATP binding protein of ABC transporter, ATPase component; Molecular function: ATP binding. Responsible for energy coupling to the transport system.
 
  
 0.437
deoR3
Putative regulatory protein, DeoR family; Transcription regulation of arabinose/xylulose/ribulose operon ?.
  
   
 0.432
CBL56198.1
Probable ABC transporter permease protein for sugars; Locus abc transport; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.424
biaA
Locus abc transport.
 
  
 0.420
ribAB
GTP cyclohydrolase II protein, Riboflavin biosynthesis protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
    
   0.414
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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