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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sseBThiosulfate + Cyanide <=> Sulfite + Thiocyanate. (272 aa)    
Predicted Functional Partners:
nirA2/sir2
Sulfite reductase [ferredoxin]; Hydrogen sulfide + 6 oxidized ferredoxin + 3 H2O = sulfite + 6 reduced ferredoxin + 6 H+.Binds 1 siroheme per subunit Binds 1 4Fe-4S cluster per subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
    
 0.929
cysH
Putative phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
    
 0.914
ldh1
L-Lactate dehydrogenase; (S)-Lactate + NAD+ <=> Pyruvate + NADH + H+; Belongs to the LDH/MDH superfamily.
   
 
  0.904
ldh2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
   
 
  0.904
CBL56121.1
NAD(P)H-dependent FMN reductase.
     
  0.900
malY
Cysteine-S-conjugate beta-lyase; L-cystathionine + H2O = L-homocysteine + NH3 + pyruvate.
     
  0.900
metB
Cystathionine gamma-synthase (O-succinylhomoserine (thiol)-lyase).
 
 
 0.892
cys1
Cysteine synthase 1; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.859
cysK
Cysteine synthase (O-acetylserine sulfhydrylase); O3-acetyl-L-serine + H2S = L-cysteine + acetate. COFACTOR: Pyridoxal phosphate Belongs to the cysteine synthase/cystathionine beta-synthase family.
  
 
 0.859
cys2
Cysteine synthase 2; Formation of cysteine from O-acetyl-serine and hydrogen sulfide. O3-acetyl-L-serine + H2S = L-cysteine + acetate; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.859
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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