node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBL57095.1 | aldB | PFREUD_15970 | PFREUD_19300 | Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis. | (S)-lactaldehyde + NAD(+) + H(2)O <=> (S)-lactate + NADH; Belongs to the aldehyde dehydrogenase family. | 0.816 |
CBL57095.1 | gadB | PFREUD_15970 | PFREUD_23230 | Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis. | L-Glutamate <=> 4-Aminobutanoate + CO2 L-Aspartate <=> beta-Alanine + CO2; Belongs to the group II decarboxylase family. | 0.912 |
CBL57095.1 | gdh | PFREUD_15970 | PFREUD_17610 | Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis. | Glutamate dehydrogenase (NAD(P)-glutamate dehydrogenase); L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH. Homohexamer (By similarity). Belongs to the Glu/Leu/Phe/Val dehydrogenases family. Evidenced as a heat stress proetin in P. freudenreichii. | 0.949 |
CBL57095.1 | glnA | PFREUD_15970 | PFREUD_16030 | Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis. | Glutamine synthetase; # ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine; Belongs to the glutamine synthetase family. | 0.919 |
CBL57095.1 | gltB | PFREUD_15970 | PFREUD_11860 | Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis. | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | 0.990 |
CBL57095.1 | gltD | PFREUD_15970 | PFREUD_11850 | Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis. | Glutamate synthase small subunit; 2 L-Glutamate + NADP+ <=> L-Glutamine + 2-Oxoglutarate + NADPH + H+. | 0.933 |
CBL57095.1 | purL/purQ | PFREUD_15970 | PFREUD_04050 | Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis. | Phosphoribosylformylglycinamidine synthase subunit PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.901 |
CBL57694.1 | aldB | PFREUD_21920 | PFREUD_19300 | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | (S)-lactaldehyde + NAD(+) + H(2)O <=> (S)-lactate + NADH; Belongs to the aldehyde dehydrogenase family. | 0.937 |
CBL57694.1 | gabT | PFREUD_21920 | PFREUD_09540 | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 4-aminobutyrate aminotransferase; 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde +; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.918 |
CBL57694.1 | gadB | PFREUD_21920 | PFREUD_23230 | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | L-Glutamate <=> 4-Aminobutanoate + CO2 L-Aspartate <=> beta-Alanine + CO2; Belongs to the group II decarboxylase family. | 0.942 |
CBL57838.1 | gadB | PFREUD_23240 | PFREUD_23230 | Glutamate/gamma-aminobutyrate anti-porter (membrane protein). | L-Glutamate <=> 4-Aminobutanoate + CO2 L-Aspartate <=> beta-Alanine + CO2; Belongs to the group II decarboxylase family. | 0.905 |
aldB | CBL57095.1 | PFREUD_19300 | PFREUD_15970 | (S)-lactaldehyde + NAD(+) + H(2)O <=> (S)-lactate + NADH; Belongs to the aldehyde dehydrogenase family. | Glutamine synthetase; Glutamate metabolism : ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine, Peptidoglycan biosynthesis. | 0.816 |
aldB | CBL57694.1 | PFREUD_19300 | PFREUD_21920 | (S)-lactaldehyde + NAD(+) + H(2)O <=> (S)-lactate + NADH; Belongs to the aldehyde dehydrogenase family. | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.937 |
aldB | gabT | PFREUD_19300 | PFREUD_09540 | (S)-lactaldehyde + NAD(+) + H(2)O <=> (S)-lactate + NADH; Belongs to the aldehyde dehydrogenase family. | 4-aminobutyrate aminotransferase; 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde +; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.937 |
aldB | gadB | PFREUD_19300 | PFREUD_23230 | (S)-lactaldehyde + NAD(+) + H(2)O <=> (S)-lactate + NADH; Belongs to the aldehyde dehydrogenase family. | L-Glutamate <=> 4-Aminobutanoate + CO2 L-Aspartate <=> beta-Alanine + CO2; Belongs to the group II decarboxylase family. | 0.916 |
aldB | gdh | PFREUD_19300 | PFREUD_17610 | (S)-lactaldehyde + NAD(+) + H(2)O <=> (S)-lactate + NADH; Belongs to the aldehyde dehydrogenase family. | Glutamate dehydrogenase (NAD(P)-glutamate dehydrogenase); L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH. Homohexamer (By similarity). Belongs to the Glu/Leu/Phe/Val dehydrogenases family. Evidenced as a heat stress proetin in P. freudenreichii. | 0.834 |
aldB | glnA | PFREUD_19300 | PFREUD_16030 | (S)-lactaldehyde + NAD(+) + H(2)O <=> (S)-lactate + NADH; Belongs to the aldehyde dehydrogenase family. | Glutamine synthetase; # ATP + L-Glutamate + NH3 <=> ADP + Orthophosphate + L-Glutamine; Belongs to the glutamine synthetase family. | 0.824 |
aldB | gltB | PFREUD_19300 | PFREUD_11860 | (S)-lactaldehyde + NAD(+) + H(2)O <=> (S)-lactate + NADH; Belongs to the aldehyde dehydrogenase family. | Glutamate synthase large subunit (Ferredoxin); 2 L-Glutamate + 2 Oxidized ferredoxin <=> L-Glutamine + 2-Oxoglutarate + 2 Reduced ferredoxin. | 0.881 |
aldB | gltD | PFREUD_19300 | PFREUD_11850 | (S)-lactaldehyde + NAD(+) + H(2)O <=> (S)-lactate + NADH; Belongs to the aldehyde dehydrogenase family. | Glutamate synthase small subunit; 2 L-Glutamate + NADP+ <=> L-Glutamine + 2-Oxoglutarate + NADPH + H+. | 0.818 |
aldB | purL/purQ | PFREUD_19300 | PFREUD_04050 | (S)-lactaldehyde + NAD(+) + H(2)O <=> (S)-lactate + NADH; Belongs to the aldehyde dehydrogenase family. | Phosphoribosylformylglycinamidine synthase subunit PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.800 |