| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaX | priA | PFREUD_20530 | PFREUD_11400 | DNA polymerase III, delta prime subunit; Deoxynucleoside triphosphate + DNA <=> Pyrophosphate + DNA. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.505 |
| dnaX | ssb | PFREUD_20530 | PFREUD_23460 | DNA polymerase III, delta prime subunit; Deoxynucleoside triphosphate + DNA <=> Pyrophosphate + DNA. | Single-strand binding protein. | 0.639 |
| dnaX | ssb2 | PFREUD_20530 | PFREUD_07960 | DNA polymerase III, delta prime subunit; Deoxynucleoside triphosphate + DNA <=> Pyrophosphate + DNA. | Single-stranded DNA-binding protein 2 (SSB 2) (Helix-destabilizing protein 2). | 0.714 |
| ftsK | ssb | PFREUD_13210 | PFREUD_23460 | DNA translocase FtsK; DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind it. Protein located at the septum. | Single-strand binding protein. | 0.683 |
| priA | dnaX | PFREUD_11400 | PFREUD_20530 | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | DNA polymerase III, delta prime subunit; Deoxynucleoside triphosphate + DNA <=> Pyrophosphate + DNA. | 0.505 |
| priA | ssb | PFREUD_11400 | PFREUD_23460 | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | Single-strand binding protein. | 0.708 |
| priA | ssb2 | PFREUD_11400 | PFREUD_07960 | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | Single-stranded DNA-binding protein 2 (SSB 2) (Helix-destabilizing protein 2). | 0.591 |
| rplI | rplJ | PFREUD_23440 | PFREUD_05570 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.989 |
| rplI | rplU | PFREUD_23440 | PFREUD_08450 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.995 |
| rplI | rpsF | PFREUD_23440 | PFREUD_23470 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.998 |
| rplI | rpsJ | PFREUD_23440 | PFREUD_05700 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.992 |
| rplI | rpsR | PFREUD_23440 | PFREUD_23450 | 50S ribosomal protein L9; Binds to the 23S rRNA. | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.999 |
| rplI | ssb | PFREUD_23440 | PFREUD_23460 | 50S ribosomal protein L9; Binds to the 23S rRNA. | Single-strand binding protein. | 0.877 |
| rplI | ssb2 | PFREUD_23440 | PFREUD_07960 | 50S ribosomal protein L9; Binds to the 23S rRNA. | Single-stranded DNA-binding protein 2 (SSB 2) (Helix-destabilizing protein 2). | 0.407 |
| rplJ | rplI | PFREUD_05570 | PFREUD_23440 | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 50S ribosomal protein L9; Binds to the 23S rRNA. | 0.989 |
| rplJ | rplU | PFREUD_05570 | PFREUD_08450 | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.989 |
| rplJ | rpsF | PFREUD_05570 | PFREUD_23470 | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.996 |
| rplJ | rpsJ | PFREUD_05570 | PFREUD_05700 | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.990 |
| rplJ | rpsR | PFREUD_05570 | PFREUD_23450 | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.990 |
| rplJ | ssb | PFREUD_05570 | PFREUD_23460 | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | Single-strand binding protein. | 0.678 |