STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBL57890.1Xanthine/uracil permease. (659 aa)    
Predicted Functional Partners:
pyrC
Dihydroorotase multifunctional complex type (dihydroorotase); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.874
pyrE
Orotate phosphoribosyltransferase (OPRT) (OPRTase); Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
  
 0.811
pyrB
Carbamoyl phosphate + L-Aspartate <=> Orthophosphate + N-Carbamoyl-L-aspartate; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
  
  
 0.784
pyrF
Orotidine 5-phosphate decarboxylase (OMP decarboxylase) (OMPDCase) (OMPdecase); Orotidine 5 prime-phosphate <=> UMP + CO2.
  
  
 0.765
carA
Carbamoyl-phosphate synthase small chain; The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides; Belongs to the CarA family.
  
  
 0.749
carB
Carbamoyl-phosphate synthase large chain (Carbamoyl-phosphate synthetase ammonia chain); 2 ATP + L-glutamine + HCO3- + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate; Binds 3 manganese ions per subunit; Belongs to the CarB family.
  
  
 0.747
cmk
Cytidylate kinase (CK) (Cytidine monophosphate kinase) (CMP kinase); Cytidylate kinase EC:2.7.4.14 catalyses the phosphorylation of cytidine 5prime-monophosphate (dCMP) to cytidine 5prime-diphosphate (dCDP) in the presence of ATP or GTP.
   
  
 0.664
CBL57325.1
Permease.
 
  
 0.620
gatA
Glutamyl-tRNA(Gln) amidotransferase subunit A (Glu-ADT subunit A); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
  
  
 0.516
guaA
GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP.
     
 0.507
Your Current Organism:
Propionibacterium freudenreichii
NCBI taxonomy Id: 754252
Other names: P. freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii ATCC 9614, Propionibacterium freudenreichii subsp. shermanii CIP 103027, Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii str. CIRM-BIA1, Propionibacterium freudenreichii subsp. shermanii strain CIRM-BIA1
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