| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBL57076.1 | CBL57937.1 | PFREUD_15780 | PFREUD_24200 | 5.2 Protein of unknown function similar to proteins from other organisms. | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.444 |
| CBL57076.1 | oxaA | PFREUD_15780 | PFREUD_24190 | 5.2 Protein of unknown function similar to proteins from other organisms. | Single-stranded nucleic acid binding R3H. | 0.713 |
| CBL57076.1 | rho | PFREUD_15780 | PFREUD_10340 | 5.2 Protein of unknown function similar to proteins from other organisms. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.449 |
| CBL57076.1 | rnpA | PFREUD_15780 | PFREUD_24210 | 5.2 Protein of unknown function similar to proteins from other organisms. | Ribonuclease P protein component (RNaseP protein) (RNase P protein) (Protein C5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.786 |
| CBL57076.1 | rplC | PFREUD_15780 | PFREUD_05710 | 5.2 Protein of unknown function similar to proteins from other organisms. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.961 |
| CBL57076.1 | rpmH | PFREUD_15780 | PFREUD_24220 | 5.2 Protein of unknown function similar to proteins from other organisms. | 6 Protein of unknown function, without similarity to other proteins; Belongs to the bacterial ribosomal protein bL34 family. | 0.878 |
| CBL57076.1 | rpsA | PFREUD_15780 | PFREUD_15330 | 5.2 Protein of unknown function similar to proteins from other organisms. | 30S ribosomal protein S1. | 0.958 |
| CBL57937.1 | CBL57076.1 | PFREUD_24200 | PFREUD_15780 | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 5.2 Protein of unknown function similar to proteins from other organisms. | 0.444 |
| CBL57937.1 | oxaA | PFREUD_24200 | PFREUD_24190 | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Single-stranded nucleic acid binding R3H. | 0.964 |
| CBL57937.1 | rho | PFREUD_24200 | PFREUD_10340 | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.661 |
| CBL57937.1 | rnpA | PFREUD_24200 | PFREUD_24210 | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Ribonuclease P protein component (RNaseP protein) (RNase P protein) (Protein C5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.987 |
| CBL57937.1 | rpmH | PFREUD_24200 | PFREUD_24220 | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 6 Protein of unknown function, without similarity to other proteins; Belongs to the bacterial ribosomal protein bL34 family. | 0.911 |
| dnaA | dnaN | PFREUD_00010 | PFREUD_00080 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.989 |
| dnaA | gidB | PFREUD_00010 | PFREUD_24170 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Methyltransferase gidB (Glucose-inhibited division protein B); Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.510 |
| dnaA | oxaA | PFREUD_00010 | PFREUD_24190 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Single-stranded nucleic acid binding R3H. | 0.472 |
| dnaA | rnpA | PFREUD_00010 | PFREUD_24210 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Ribonuclease P protein component (RNaseP protein) (RNase P protein) (Protein C5); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.829 |
| dnaA | rpmH | PFREUD_00010 | PFREUD_24220 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 6 Protein of unknown function, without similarity to other proteins; Belongs to the bacterial ribosomal protein bL34 family. | 0.783 |
| dnaN | dnaA | PFREUD_00080 | PFREUD_00010 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.989 |
| dnaN | gidB | PFREUD_00080 | PFREUD_24170 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Methyltransferase gidB (Glucose-inhibited division protein B); Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.558 |
| dnaN | oxaA | PFREUD_00080 | PFREUD_24190 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Single-stranded nucleic acid binding R3H. | 0.525 |
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