STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q7C_331Two-component system sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (432 aa)    
Predicted Functional Partners:
Q7C_117
Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Biotin-requiring enzyme; TIGRFAM: dihydrolipoamide dehydrogenase.
   
 0.914
Q7C_330
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
   0.841
Q7C_333
Putative membrane protein; PFAM: Protein of unknown function (DUF1295).
 
     0.839
Q7C_334
PFAM: Protein of unknown function (DUF2878).
 
     0.834
Q7C_338
PFAM: Fatty acid desaturase.
 
     0.829
Q7C_336
PFAM: Protein of unknown function (DUF1365).
 
     0.817
Q7C_332
Cyclopropane-fatty-acyl-phospholipid synthase-like protein; PFAM: Cyclopropane-fatty-acyl-phospholipid synthase.
 
     0.813
Q7C_337
Amine oxidase; PFAM: Flavin containing amine oxidoreductase.
       0.788
Q7C_335
S-adenosyl-L-methionine dependent methyltransferase; PFAM: Cyclopropane-fatty-acyl-phospholipid synthase.
       0.780
Q7C_424
Copper-sensing two-component system response regulator CpxR; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
   0.770
Your Current Organism:
Methylophaga frappieri
NCBI taxonomy Id: 754477
Other names: ATCC BAA-2434, DSM 25690, M. frappieri, Methylophaga frappieri Villeneuve et al. 2013, Methylophaga sp. JAM7, strain JAM7
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